BDBM50195881 3-(4-methoxyphenyl)-7-(3,4,5-trimethoxyphenyl)thieno[3,2-c]pyridin-4-amine::CHEMBL396912

SMILES: COc1ccc(cc1)-c1csc2c(cnc(N)c12)-c1cc(OC)c(OC)c(OC)c1

InChI Key: InChIKey=FFSDAFXAJFTFNV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50195881   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50195881 (3-(4-methoxyphenyl)-7-(3,4,5-trimethoxyphenyl)thie...) Show SMILES COc1ccc(cc1)-c1csc2c(cnc(N)c12)-c1cc(OC)c(OC)c(OC)c1 Show InChI InChI=1S/C23H22N2O4S/c1-26-15-7-5-13(6-8-15)17-12-30-22-16(11-25-23(24)20(17)22)14-9-18(27-2)21(29-4)19(10-14)28-3/h5-12H,1-4H3,(H2,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline K.K. Curated by ChEMBL					Assay Description Inhibition of human EphB4 by scintillation proximity method				Bioorg Med Chem Lett 17: 250-4 (2006) Article DOI: 10.1016/j.bmcl.2006.09.050 BindingDB Entry DOI: 10.7270/Q2SB45D5
					More data for this Ligand-Target Pair