BDBM50195887 3-bromo-7-(3,4,5-trimethoxyphenyl)thieno[3,2-c]pyridin-4-amine::CHEMBL247696

SMILES: COc1cc(cc(OC)c1OC)-c1cnc(N)c2c(Br)csc12

InChI Key: InChIKey=TWLCHRPTWCVAEB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50195887   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50195887 (3-bromo-7-(3,4,5-trimethoxyphenyl)thieno[3,2-c]pyr...) Show SMILES COc1cc(cc(OC)c1OC)-c1cnc(N)c2c(Br)csc12 Show InChI InChI=1S/C16H15BrN2O3S/c1-20-11-4-8(5-12(21-2)14(11)22-3)9-6-19-16(18)13-10(17)7-23-15(9)13/h4-7H,1-3H3,(H2,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline K.K. Curated by ChEMBL					Assay Description Inhibition of human EphB4 by scintillation proximity method				Bioorg Med Chem Lett 17: 250-4 (2006) Article DOI: 10.1016/j.bmcl.2006.09.050 BindingDB Entry DOI: 10.7270/Q2SB45D5
					More data for this Ligand-Target Pair