BDBM50195894 1-(4-(4-amino-7-(3,4,5-trimethoxyphenyl)thieno[3,2-c]pyridin-3-yl)phenyl)ethanone::CHEMBL394383

SMILES: COc1cc(cc(OC)c1OC)-c1cnc(N)c2c(csc12)-c1ccc(cc1)C(C)=O

InChI Key: InChIKey=LMNFJUCPNXRSEZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50195894   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50195894 (1-(4-(4-amino-7-(3,4,5-trimethoxyphenyl)thieno[3,2...) Show SMILES COc1cc(cc(OC)c1OC)-c1cnc(N)c2c(csc12)-c1ccc(cc1)C(C)=O Show InChI InChI=1S/C24H22N2O4S/c1-13(27)14-5-7-15(8-6-14)18-12-31-23-17(11-26-24(25)21(18)23)16-9-19(28-2)22(30-4)20(10-16)29-3/h5-12H,1-4H3,(H2,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline K.K. Curated by ChEMBL					Assay Description Inhibition of human EphB4 by scintillation proximity method				Bioorg Med Chem Lett 17: 250-4 (2006) Article DOI: 10.1016/j.bmcl.2006.09.050 BindingDB Entry DOI: 10.7270/Q2SB45D5
					More data for this Ligand-Target Pair