BDBM50196341 2-((3-(2-bromo-4-hydroxy-5-methoxybenzyl)thioureido)methyl)-3-(4-tert-butylphenyl)propyl pivalate::CHEMBL239386

SMILES: COc1cc(CNC(=S)NCC(COC(=O)C(C)(C)C)Cc2ccc(cc2)C(C)(C)C)c(Br)cc1O

InChI Key: InChIKey=NDSRMXCGPBRPGD-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50196341   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vanilloid receptor (Rattus norvegicus (rat))	BDBM50196341 (2-((3-(2-bromo-4-hydroxy-5-methoxybenzyl)thioureid...) Show SMILES COc1cc(CNC(=S)NCC(COC(=O)C(C)(C)C)Cc2ccc(cc2)C(C)(C)C)c(Br)cc1O Show InChI InChI=1S/C28H39BrN2O4S/c1-27(2,3)21-10-8-18(9-11-21)12-19(17-35-25(33)28(4,5)6)15-30-26(36)31-16-20-13-24(34-7)23(32)14-22(20)29/h8-11,13-14,19,32H,12,15-17H2,1-7H3,(H2,30,31,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [3H]RTX from rat TRPV1 expressed in CHO cells				Bioorg Med Chem Lett 17: 214-9 (2006) Article DOI: 10.1016/j.bmcl.2006.09.059 BindingDB Entry DOI: 10.7270/Q27D2TSX
					More data for this Ligand-Target Pair
Vanilloid receptor (Rattus norvegicus (rat))	BDBM50196341 (2-((3-(2-bromo-4-hydroxy-5-methoxybenzyl)thioureid...) Show SMILES COc1cc(CNC(=S)NCC(COC(=O)C(C)(C)C)Cc2ccc(cc2)C(C)(C)C)c(Br)cc1O Show InChI InChI=1S/C28H39BrN2O4S/c1-27(2,3)21-10-8-18(9-11-21)12-19(17-35-25(33)28(4,5)6)15-30-26(36)31-16-20-13-24(34-7)23(32)14-22(20)29/h8-11,13-14,19,32H,12,15-17H2,1-7H3,(H2,30,31,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in CHO cells assessed as inhibition of calcium uptake				Bioorg Med Chem Lett 17: 214-9 (2006) Article DOI: 10.1016/j.bmcl.2006.09.059 BindingDB Entry DOI: 10.7270/Q27D2TSX
					More data for this Ligand-Target Pair