BDBM50196493 (N,N0-bis[2-(1-piperidino)ethyl]-3,4,9,10-perylenetetracarboxylic diimide::2,9-Bis-(2-piperidin-1-yl-ethyl)-anthra[2,1,9-def;6,5,10-d'e'f']diisoquinoline-1,3,8,10-tetraone::CHEMBL359594::Piper
SMILES: O=c1n(CCN2CCCCC2)c(=O)c2ccc3c4ccc5c6c(ccc(c7ccc1c2c37)c46)c(=O)n(CCN1CCCCC1)c5=O
InChI Key: InChIKey=GEJMGGZVFDIQCA-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Taq polymerase 1 (Thermus aquaticus) | BDBM50196493 ((N,N0-bis[2-(1-piperidino)ethyl]-3,4,9,10-perylene...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Padova Curated by ChEMBL | Assay Description Inhibition of Taq polymerase | Bioorg Med Chem 15: 555-62 (2006) Article DOI: 10.1016/j.bmc.2006.09.029 BindingDB Entry DOI: 10.7270/Q2QC033H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Telomerase reverse transcriptase (Homo sapiens (Human)) | BDBM50196493 ((N,N0-bis[2-(1-piperidino)ethyl]-3,4,9,10-perylene...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Padova Curated by ChEMBL | Assay Description Inhibition of telomerase in JR8 cell extract by TRAP assay | Bioorg Med Chem 15: 555-62 (2006) Article DOI: 10.1016/j.bmc.2006.09.029 BindingDB Entry DOI: 10.7270/Q2QC033H | |||||||||||
More data for this Ligand-Target Pair |