BDBM50196513 CHEMBL3964362

SMILES: N\C(=N/O)c1ccc(NC(=O)CCCCNCCc2ccccc2)cc1

InChI Key: InChIKey=MXGWWEJKHMLSRD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50196513   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase (HDAC1 and HDAC2) (Homo sapiens (Human))	BDBM50196513 (CHEMBL3964362) Show SMILES N\C(=N/O)c1ccc(NC(=O)CCCCNCCc2ccccc2)cc1 Show InChI InChI=1S/C20H26N4O2/c21-20(24-26)17-9-11-18(12-10-17)23-19(25)8-4-5-14-22-15-13-16-6-2-1-3-7-16/h1-3,6-7,9-12,22,26H,4-5,8,13-15H2,(H2,21,24)(H,23,25)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Qilu Normal University Curated by ChEMBL					Assay Description Inhibition of HDAC1/HDAC2 in human HeLa cell nuclear extract preincubated for 20 mins followed by addition of HDAC green as substrate measured after ...				Bioorg Med Chem Lett 26: 4679-4683 (2016) Article DOI: 10.1016/j.bmcl.2016.08.073 BindingDB Entry DOI: 10.7270/Q2V69MKX
					More data for this Ligand-Target Pair