BDBM50196691 CHEMBL389915::N-(1-(4-nitrobenzyl)piperidin-3-yl)-1H-indazol-5-amine::N-[1-(4-nitrobenzyl)-3-piperidyl]-N-(1H-5-indazolyl)amine

SMILES: [O-][N+](=O)c1ccc(CN2CCCC(C2)Nc2ccc3[nH]ncc3c2)cc1

InChI Key: InChIKey=OUOPQLSJLBGMFE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50196691   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2/Rho-kinase (ROCK I) (Homo sapiens (Human))	BDBM50196691 (CHEMBL389915 | N-(1-(4-nitrobenzyl)piperidin-3-yl)...) Show SMILES [O-][N+](=O)c1ccc(CN2CCCC(C2)Nc2ccc3[nH]ncc3c2)cc1 Show InChI InChI=1S/C19H21N5O2/c25-24(26)18-6-3-14(4-7-18)12-23-9-1-2-17(13-23)21-16-5-8-19-15(10-16)11-20-22-19/h3-8,10-11,17,21H,1-2,9,12-13H2,(H,20,22)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
Kirin Brewery Co. Ltd Curated by ChEMBL					Assay Description Inhibition of Rho kinase				Bioorg Med Chem 15: 350-64 (2006) Article DOI: 10.1016/j.bmc.2006.09.052 BindingDB Entry DOI: 10.7270/Q2T43TW5
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50196691 (CHEMBL389915 | N-(1-(4-nitrobenzyl)piperidin-3-yl)...) Show SMILES [O-][N+](=O)c1ccc(CN2CCCC(C2)Nc2ccc3[nH]ncc3c2)cc1 Show InChI InChI=1S/C19H21N5O2/c25-24(26)18-6-3-14(4-7-18)12-23-9-1-2-17(13-23)21-16-5-8-19-15(10-16)11-20-22-19/h3-8,10-11,17,21H,1-2,9,12-13H2,(H,20,22)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kirin Brewery Co. Ltd Curated by ChEMBL					Assay Description Inhibition of MCP1-induced cell migration in U937 cells expressing CCR2 by chemotaxis assay				Bioorg Med Chem 15: 350-64 (2006) Article DOI: 10.1016/j.bmc.2006.09.052 BindingDB Entry DOI: 10.7270/Q2T43TW5
					More data for this Ligand-Target Pair