BDBM50197005 CHEMBL436821::N-[4-{2-[2-(2-{2-[4-(3,5-dioxo-hexyl)-phenylcarbamoyl]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-2'-(isoxazol-5-ylsulfamoyl)-biphenyl-2-ylmethyl]-3,3,N-trimethyl-butyramide

SMILES: CN(Cc1cc(OCCOCCOCCOCCC(=O)Nc2ccc(CCC(=O)CC(C)=O)cc2)ccc1-c1ccccc1S(=O)(=O)Nc1ccno1)C(=O)CC(C)(C)C

InChI Key: InChIKey=MGOQYQRCURWWNQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50197005   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50197005 (CHEMBL436821 | N-[4-{2-[2-(2-{2-[4-(3,5-dioxo-hexy...) Show SMILES CN(Cc1cc(OCCOCCOCCOCCC(=O)Nc2ccc(CCC(=O)CC(C)=O)cc2)ccc1-c1ccccc1S(=O)(=O)Nc1ccno1)C(=O)CC(C)(C)C Show InChI InChI=1S/C44H56N4O11S/c1-32(49)28-36(50)15-12-33-10-13-35(14-11-33)46-41(51)19-21-55-22-23-56-24-25-57-26-27-58-37-16-17-38(34(29-37)31-48(5)43(52)30-44(2,3)4)39-8-6-7-9-40(39)60(53,54)47-42-18-20-45-59-42/h6-11,13-14,16-18,20,29,47H,12,15,19,21-28,30-31H2,1-5H3,(H,46,51)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	44.9	n/a	n/a	n/a	n/a	n/a	n/a
CovX Research LLC Curated by ChEMBL					Assay Description Displacement of [125I]ET1 from human ETA receptor expressed in CHO cells				Bioorg Med Chem Lett 17: 501-6 (2007) Article DOI: 10.1016/j.bmcl.2006.10.009 BindingDB Entry DOI: 10.7270/Q2DZ07ZF
					More data for this Ligand-Target Pair
EDNRB (Homo sapiens (Human))	BDBM50197005 (CHEMBL436821 | N-[4-{2-[2-(2-{2-[4-(3,5-dioxo-hexy...) Show SMILES CN(Cc1cc(OCCOCCOCCOCCC(=O)Nc2ccc(CCC(=O)CC(C)=O)cc2)ccc1-c1ccccc1S(=O)(=O)Nc1ccno1)C(=O)CC(C)(C)C Show InChI InChI=1S/C44H56N4O11S/c1-32(49)28-36(50)15-12-33-10-13-35(14-11-33)46-41(51)19-21-55-22-23-56-24-25-57-26-27-58-37-16-17-38(34(29-37)31-48(5)43(52)30-44(2,3)4)39-8-6-7-9-40(39)60(53,54)47-42-18-20-45-59-42/h6-11,13-14,16-18,20,29,47H,12,15,19,21-28,30-31H2,1-5H3,(H,46,51)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
CovX Research LLC Curated by ChEMBL					Assay Description Displacement of [125I]ET1 from human ETB receptor expressed in CHO cells				Bioorg Med Chem Lett 17: 501-6 (2007) Article DOI: 10.1016/j.bmcl.2006.10.009 BindingDB Entry DOI: 10.7270/Q2DZ07ZF
					More data for this Ligand-Target Pair