Found 6 hits for monomerid = 50197040 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM50197040
(CHEMBL3894651)Show SMILES N[C@@H](C(NS(=O)(=O)c1cccc(c1)C(F)(F)F)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C11H11F3N2O6S/c12-11(13,14)5-2-1-3-6(4-5)23(21,22)16-8(10(19)20)7(15)9(17)18/h1-4,7-8,16H,15H2,(H,17,18)(H,19,20)/t7-,8?/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG MMDB PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.58E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT3 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 1
(Homo sapiens (Human)) | BDBM50197040
(CHEMBL3894651)Show SMILES N[C@@H](C(NS(=O)(=O)c1cccc(c1)C(F)(F)F)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C11H11F3N2O6S/c12-11(13,14)5-2-1-3-6(4-5)23(21,22)16-8(10(19)20)7(15)9(17)18/h1-4,7-8,16H,15H2,(H,17,18)(H,19,20)/t7-,8?/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG MMDB PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT1 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 2
(Homo sapiens (Human)) | BDBM50197040
(CHEMBL3894651)Show SMILES N[C@@H](C(NS(=O)(=O)c1cccc(c1)C(F)(F)F)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C11H11F3N2O6S/c12-11(13,14)5-2-1-3-6(4-5)23(21,22)16-8(10(19)20)7(15)9(17)18/h1-4,7-8,16H,15H2,(H,17,18)(H,19,20)/t7-,8?/m0/s1 | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG MMDB PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.75E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT2 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM50197040
(CHEMBL3894651)Show SMILES N[C@@H](C(NS(=O)(=O)c1cccc(c1)C(F)(F)F)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C11H11F3N2O6S/c12-11(13,14)5-2-1-3-6(4-5)23(21,22)16-8(10(19)20)7(15)9(17)18/h1-4,7-8,16H,15H2,(H,17,18)(H,19,20)/t7-,8?/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG MMDB PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT3 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 1
(Homo sapiens (Human)) | BDBM50197040
(CHEMBL3894651)Show SMILES N[C@@H](C(NS(=O)(=O)c1cccc(c1)C(F)(F)F)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C11H11F3N2O6S/c12-11(13,14)5-2-1-3-6(4-5)23(21,22)16-8(10(19)20)7(15)9(17)18/h1-4,7-8,16H,15H2,(H,17,18)(H,19,20)/t7-,8?/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG MMDB PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT1 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 2
(Homo sapiens (Human)) | BDBM50197040
(CHEMBL3894651)Show SMILES N[C@@H](C(NS(=O)(=O)c1cccc(c1)C(F)(F)F)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C11H11F3N2O6S/c12-11(13,14)5-2-1-3-6(4-5)23(21,22)16-8(10(19)20)7(15)9(17)18/h1-4,7-8,16H,15H2,(H,17,18)(H,19,20)/t7-,8?/m0/s1 | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG MMDB PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT2 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |