BDBM50197061 CHEMBL3965023

SMILES: CC(C)(C)c1cccc(Nc2ccccc2-c2nnn[nH]2)c1

InChI Key: InChIKey=UVQQSBCPOHKBSX-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50197061   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium channel subfamily K member 18 (Homo sapiens (Human))	BDBM50197061 (CHEMBL3965023) Show SMILES CC(C)(C)c1cccc(Nc2ccccc2-c2nnn[nH]2)c1 Show InChI InChI=1S/C17H19N5/c1-17(2,3)12-7-6-8-13(11-12)18-15-10-5-4-9-14(15)16-19-21-22-20-16/h4-11,18H,1-3H3,(H,19,20,21,22)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.88E+4	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Activation of human TRESK channel expressed in HEK293 cells assessed as induction of channel current by whole cell patch clamp assay				Bioorg Med Chem Lett 26: 4919-4924 (2016) Article DOI: 10.1016/j.bmcl.2016.09.020 BindingDB Entry DOI: 10.7270/Q2T72KDN
					More data for this Ligand-Target Pair