null

SMILES: CC#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c1ccc(cc1)N(C)CC(=O)Nc1nc(CC(O)=O)cs1

InChI Key: InChIKey=UDHISUQCHJCRAL-FOTGZYITSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50197430   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50197430 (CHEMBL245267 | [2-(2-{[4-((9S,11R,13S,14S,17S)-17-...) Show SMILES CC#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c1ccc(cc1)N(C)CC(=O)Nc1nc(CC(O)=O)cs1 |c:18,t:11| Show InChI InChI=1S/C35H39N3O5S/c1-4-14-35(43)15-13-29-27-11-7-22-16-25(39)10-12-26(22)32(27)28(18-34(29,35)2)21-5-8-24(9-6-21)38(3)19-30(40)37-33-36-23(20-44-33)17-31(41)42/h5-6,8-9,16,20,27-29,43H,7,10-13,15,17-19H2,1-3H3,(H,41,42)(H,36,37,40)/t27-,28+,29-,34-,35-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human GR transcriptional activation by HepTAT cells				Bioorg Med Chem Lett 17: 40-4 (2006) Article DOI: 10.1016/j.bmcl.2006.10.001 BindingDB Entry DOI: 10.7270/Q2DR2W9G
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50197430 (CHEMBL245267 | [2-(2-{[4-((9S,11R,13S,14S,17S)-17-...) Show SMILES CC#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c1ccc(cc1)N(C)CC(=O)Nc1nc(CC(O)=O)cs1 |c:18,t:11| Show InChI InChI=1S/C35H39N3O5S/c1-4-14-35(43)15-13-29-27-11-7-22-16-25(39)10-12-26(22)32(27)28(18-34(29,35)2)21-5-8-24(9-6-21)38(3)19-30(40)37-33-36-23(20-44-33)17-31(41)42/h5-6,8-9,16,20,27-29,43H,7,10-13,15,17-19H2,1-3H3,(H,41,42)(H,36,37,40)/t27-,28+,29-,34-,35-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of radiolabeled Dexamethasone from human GR				Bioorg Med Chem Lett 17: 40-4 (2006) Article DOI: 10.1016/j.bmcl.2006.10.001 BindingDB Entry DOI: 10.7270/Q2DR2W9G
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50197430 (CHEMBL245267 | [2-(2-{[4-((9S,11R,13S,14S,17S)-17-...) Show SMILES CC#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c1ccc(cc1)N(C)CC(=O)Nc1nc(CC(O)=O)cs1 |c:18,t:11| Show InChI InChI=1S/C35H39N3O5S/c1-4-14-35(43)15-13-29-27-11-7-22-16-25(39)10-12-26(22)32(27)28(18-34(29,35)2)21-5-8-24(9-6-21)38(3)19-30(40)37-33-36-23(20-44-33)17-31(41)42/h5-6,8-9,16,20,27-29,43H,7,10-13,15,17-19H2,1-3H3,(H,41,42)(H,36,37,40)/t27-,28+,29-,34-,35-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	765	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human GR expressed in hGRAF cells				Bioorg Med Chem Lett 17: 40-4 (2006) Article DOI: 10.1016/j.bmcl.2006.10.001 BindingDB Entry DOI: 10.7270/Q2DR2W9G
					More data for this Ligand-Target Pair