BDBM50197538 CHEMBL3915923

SMILES: CC(C)[C@H](NS(=O)(=O)N[C@@H](CCCCN)C(O)=O)C(=O)NC12CC3CC(CC(C3)C1)C2

InChI Key: InChIKey=OUNNZIYXVZDQEH-OITRNQOZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50197538   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carboxypeptidase B2 isoform A (Homo sapiens (Human))	BDBM50197538 (CHEMBL3915923) Show SMILES CC(C)[C@H](NS(=O)(=O)N[C@@H](CCCCN)C(O)=O)C(=O)NC12CC3CC(CC(C3)C1)C2 |r,TLB:20:21:24:28.27.26,THB:22:21:24.23.28:26,22:23:26:30.21.29,29:21:24:28.27.26,29:27:24:30.21.22| Show InChI InChI=1S/C21H38N4O5S/c1-13(2)18(25-31(29,30)24-17(20(27)28)5-3-4-6-22)19(26)23-21-10-14-7-15(11-21)9-16(8-14)12-21/h13-18,24-25H,3-12,22H2,1-2H3,(H,23,26)(H,27,28)/t14?,15?,16?,17-,18-,21?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi R&D Curated by ChEMBL					Assay Description Inhibition of activated human plasma TAFI incubated for 15 mins in presence of 1% human serum albumin by chromogenic assay				J Med Chem 59: 9567-9573 (2016) Article DOI: 10.1021/acs.jmedchem.6b01276 BindingDB Entry DOI: 10.7270/Q2MG7RG2
					More data for this Ligand-Target Pair