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BDBM50197859 4-butyl-N-(3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)benzenesulfonamide::CHEMBL231334

SMILES: CCCCc1ccc(cc1)S(=O)(=O)Nc1ccc2CCN(C)CCc2c1

InChI Key: InChIKey=GGAQZJOAVWSKSS-UHFFFAOYSA-N

Data: 5 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50197859
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50197859 (4-butyl-N-(3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
UK. Vinc Curated by ChEMBL					Assay Description Inhibition of CYP3A4				Bioorg Med Chem Lett 17: 400-5 (2007) Article DOI: 10.1016/j.bmcl.2006.10.036 BindingDB Entry DOI: 10.7270/Q2668CVB
UK. Vinc Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50197859 (4-butyl-N-(3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
UK. Vinc Curated by ChEMBL					Assay Description Inhibition of CYP2C9				Bioorg Med Chem Lett 17: 400-5 (2007) Article DOI: 10.1016/j.bmcl.2006.10.036 BindingDB Entry DOI: 10.7270/Q2668CVB
UK. Vinc Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 1A2 (Homo sapiens (Human))	BDBM50197859 (4-butyl-N-(3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
UK. Vinc Curated by ChEMBL					Assay Description Inhibition of CYP1A2				Bioorg Med Chem Lett 17: 400-5 (2007) Article DOI: 10.1016/j.bmcl.2006.10.036 BindingDB Entry DOI: 10.7270/Q2668CVB
UK. Vinc Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM50197859 (4-butyl-N-(3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
UK. Vinc Curated by ChEMBL					Assay Description Inhibition of CYP2C19				Bioorg Med Chem Lett 17: 400-5 (2007) Article DOI: 10.1016/j.bmcl.2006.10.036 BindingDB Entry DOI: 10.7270/Q2668CVB
UK. Vinc Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50197859 (4-butyl-N-(3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]...) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
UK. Vinc Curated by ChEMBL					Assay Description Inhibition of CYP2D6				Bioorg Med Chem Lett 17: 400-5 (2007) Article DOI: 10.1016/j.bmcl.2006.10.036 BindingDB Entry DOI: 10.7270/Q2668CVB
UK. Vinc Curated by ChEMBL					More data for this Ligand-Target Pair