BDBM50198196 CHEMBL3898463

SMILES: [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6@@H]1-[#6][C@@]2([#6]\[#6]=[#6](/[#6])-[#6])[#6](-[#8])=[#6](-[#6]3-[#8]-[#6@H](-[#6]-[#6][C@]1([#6])[C@@]3([#6]\[#6]=[#6](\[#6])-[#6])[#6]2=O)C([#6])([#6])[#8])-[#6](=O)-c1ccc(-[#8])c(-[#8])c1

InChI Key: InChIKey=HDPSOTGMCLJKNZ-YIDRXNJSSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50198196   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA polymerase lambda (Homo sapiens (Human))	BDBM50198196 (CHEMBL3898463) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6@@H]1-[#6][C@@]2([#6]\[#6]=[#6](/[#6])-[#6])[#6](-[#8])=[#6](-[#6]3-[#8]-[#6@H](-[#6]-[#6][C@]1([#6])[C@@]3([#6]\[#6]=[#6](\[#6])-[#6])[#6]2=O)C([#6])([#6])[#8])-[#6](=O)-c1ccc(-[#8])c(-[#8])c1 |r,c:19,THB:35:34:11.10.26:20.18.21| Show InChI InChI=1S/C43H60O7/c1-26(2)12-11-13-29(7)14-16-31-25-42(22-18-27(3)4)37(47)35(36(46)30-15-17-32(44)33(45)24-30)38-43(39(42)48,23-19-28(5)6)41(31,10)21-20-34(50-38)40(8,9)49/h12,14-15,17-19,24,31,34,38,44-45,47,49H,11,13,16,20-23,25H2,1-10H3/b29-14+/t31-,34-,38?,41+,42+,43-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human His-tagged DNA polymerase lambda assessed as reduction in [3H]dTTP incorporation using poly(dA)/oligo(dT)18 as templa...				J Nat Prod 79: 1798-807 (2016) Article DOI: 10.1021/acs.jnatprod.6b00255 BindingDB Entry DOI: 10.7270/Q2930W5F
					More data for this Ligand-Target Pair