null

SMILES: COc1ccccc1OC(C1CNCCO1)c1ccc(I)s1

InChI Key: InChIKey=TUMPGFWCYJFORL-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50198228   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transporter (Rattus norvegicus)	BDBM50198228 (2-((5-iodothiophen-2-yl)(2-methoxyphenoxy)methyl)m...) Show SMILES COc1ccccc1OC(C1CNCCO1)c1ccc(I)s1 |w:10.16,9.9| Show InChI InChI=1S/C16H18INO3S/c1-19-11-4-2-3-5-12(11)21-16(13-10-18-8-9-20-13)14-6-7-15(17)22-14/h2-7,13,16,18H,8-10H2,1H3	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	79.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Degenerative Diseases Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from NET in rat brain membranes				Bioorg Med Chem Lett 17: 533-7 (2007) Article DOI: 10.1016/j.bmcl.2006.10.018 BindingDB Entry DOI: 10.7270/Q2WS8SX8
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50198228 (2-((5-iodothiophen-2-yl)(2-methoxyphenoxy)methyl)m...) Show SMILES COc1ccccc1OC(C1CNCCO1)c1ccc(I)s1 |w:10.16,9.9| Show InChI InChI=1S/C16H18INO3S/c1-19-11-4-2-3-5-12(11)21-16(13-10-18-8-9-20-13)14-6-7-15(17)22-14/h2-7,13,16,18H,8-10H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	141	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Degenerative Diseases Curated by ChEMBL					Assay Description Displacement of [3H]paroxetine from SERT in brain membranes				Bioorg Med Chem Lett 17: 533-7 (2007) Article DOI: 10.1016/j.bmcl.2006.10.018 BindingDB Entry DOI: 10.7270/Q2WS8SX8
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50198228 (2-((5-iodothiophen-2-yl)(2-methoxyphenoxy)methyl)m...) Show SMILES COc1ccccc1OC(C1CNCCO1)c1ccc(I)s1 |w:10.16,9.9| Show InChI InChI=1S/C16H18INO3S/c1-19-11-4-2-3-5-12(11)21-16(13-10-18-8-9-20-13)14-6-7-15(17)22-14/h2-7,13,16,18H,8-10H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Degenerative Diseases Curated by ChEMBL					Assay Description Displacement of [3H]GBR from DAT in rat brain membranes				Bioorg Med Chem Lett 17: 533-7 (2007) Article DOI: 10.1016/j.bmcl.2006.10.018 BindingDB Entry DOI: 10.7270/Q2WS8SX8
					More data for this Ligand-Target Pair