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SMILES: FC(F)(F)c1ccccc1OC(C1CNCCO1)c1cccc(I)c1

InChI Key: InChIKey=SQWQWSORIRRKHB-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50198229   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transporter (Rattus norvegicus)	BDBM50198229 (2-((3-iodophenyl)(2-(trifluoromethyl)phenoxy)methy...) Show SMILES FC(F)(F)c1ccccc1OC(C1CNCCO1)c1cccc(I)c1 |w:12.13,11.11| Show InChI InChI=1S/C18H17F3INO2/c19-18(20,21)14-6-1-2-7-15(14)25-17(16-11-23-8-9-24-16)12-4-3-5-13(22)10-12/h1-7,10,16-17,23H,8-9,11H2	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	101	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Degenerative Diseases Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from NET in rat brain membranes				Bioorg Med Chem Lett 17: 533-7 (2007) Article DOI: 10.1016/j.bmcl.2006.10.018 BindingDB Entry DOI: 10.7270/Q2WS8SX8
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50198229 (2-((3-iodophenyl)(2-(trifluoromethyl)phenoxy)methy...) Show SMILES FC(F)(F)c1ccccc1OC(C1CNCCO1)c1cccc(I)c1 |w:12.13,11.11| Show InChI InChI=1S/C18H17F3INO2/c19-18(20,21)14-6-1-2-7-15(14)25-17(16-11-23-8-9-24-16)12-4-3-5-13(22)10-12/h1-7,10,16-17,23H,8-9,11H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	486	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Degenerative Diseases Curated by ChEMBL					Assay Description Displacement of [3H]paroxetine from SERT in brain membranes				Bioorg Med Chem Lett 17: 533-7 (2007) Article DOI: 10.1016/j.bmcl.2006.10.018 BindingDB Entry DOI: 10.7270/Q2WS8SX8
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50198229 (2-((3-iodophenyl)(2-(trifluoromethyl)phenoxy)methy...) Show SMILES FC(F)(F)c1ccccc1OC(C1CNCCO1)c1cccc(I)c1 |w:12.13,11.11| Show InChI InChI=1S/C18H17F3INO2/c19-18(20,21)14-6-1-2-7-15(14)25-17(16-11-23-8-9-24-16)12-4-3-5-13(22)10-12/h1-7,10,16-17,23H,8-9,11H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.87E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Degenerative Diseases Curated by ChEMBL					Assay Description Displacement of [3H]GBR from DAT in rat brain membranes				Bioorg Med Chem Lett 17: 533-7 (2007) Article DOI: 10.1016/j.bmcl.2006.10.018 BindingDB Entry DOI: 10.7270/Q2WS8SX8
					More data for this Ligand-Target Pair