BDBM50198341 CHEMBL3948172

SMILES: CC1CCCC2(O1)OC(O)C=CC2=O

InChI Key: InChIKey=VQPCEYJOGDXUFW-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50198341   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50198341 (CHEMBL3948172) Show SMILES CC1CCCC2(O1)OC(O)C=CC2=O |c:11| Show InChI InChI=1S/C10H14O4/c1-7-3-2-6-10(13-7)8(11)4-5-9(12)14-10/h4-5,7,9,12H,2-3,6H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Farmacologia Traslazionale Curated by ChEMBL					Assay Description Inhibition of telomerase activity in human MCF7 cells using biotin-labeled TeloTAGGG as primer preincubated for 48 hrs followed by primer addition me...				J Med Chem 59: 9140-9149 (2016) Article DOI: 10.1021/acs.jmedchem.6b01046 BindingDB Entry DOI: 10.7270/Q2NC6352
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50198341 (CHEMBL3948172) Show SMILES CC1CCCC2(O1)OC(O)C=CC2=O |c:11| Show InChI InChI=1S/C10H14O4/c1-7-3-2-6-10(13-7)8(11)4-5-9(12)14-10/h4-5,7,9,12H,2-3,6H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Farmacologia Traslazionale Curated by ChEMBL					Assay Description Inhibition of telomerase activity in human M14 cells using biotin-labeled TeloTAGGG as primer preincubated for 48 hrs followed by primer addition mea...				J Med Chem 59: 9140-9149 (2016) Article DOI: 10.1021/acs.jmedchem.6b01046 BindingDB Entry DOI: 10.7270/Q2NC6352
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50198341 (CHEMBL3948172) Show SMILES CC1CCCC2(O1)OC(O)C=CC2=O |c:11| Show InChI InChI=1S/C10H14O4/c1-7-3-2-6-10(13-7)8(11)4-5-9(12)14-10/h4-5,7,9,12H,2-3,6H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Farmacologia Traslazionale Curated by ChEMBL					Assay Description Inhibition of telomerase activity in human HT-29 cells using biotin-labeled TeloTAGGG as primer preincubated for 48 hrs followed by primer addition m...				J Med Chem 59: 9140-9149 (2016) Article DOI: 10.1021/acs.jmedchem.6b01046 BindingDB Entry DOI: 10.7270/Q2NC6352
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50198341 (CHEMBL3948172) Show SMILES CC1CCCC2(O1)OC(O)C=CC2=O |c:11| Show InChI InChI=1S/C10H14O4/c1-7-3-2-6-10(13-7)8(11)4-5-9(12)14-10/h4-5,7,9,12H,2-3,6H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Farmacologia Traslazionale Curated by ChEMBL					Assay Description Inhibition of telomerase activity in human H125 cells using biotin-labeled TeloTAGGG as primer preincubated for 48 hrs followed by primer addition me...				J Med Chem 59: 9140-9149 (2016) Article DOI: 10.1021/acs.jmedchem.6b01046 BindingDB Entry DOI: 10.7270/Q2NC6352
					More data for this Ligand-Target Pair