BDBM50198540 (R)-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)benzylamino)pentan-2-yl)benzofuran-2-carboxamide::CHEMBL216241

SMILES: NC(=N)NCCC[C@@H](NC(=O)c1cc2ccccc2o1)C(=O)NCc1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=LQTCSCNXEYUNQI-QGZVFWFLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50198540   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50198540 ((R)-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)ben...) Show SMILES NC(=N)NCCC[C@@H](NC(=O)c1cc2ccccc2o1)C(=O)NCc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C23H24F3N5O3/c24-23(25,26)16-9-7-14(8-10-16)13-30-20(32)17(5-3-11-29-22(27)28)31-21(33)19-12-15-4-1-2-6-18(15)34-19/h1-2,4,6-10,12,17H,3,5,11,13H2,(H,30,32)(H,31,33)(H4,27,28,29)/t17-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	313	n/a	n/a	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Functional antagonism of MCH-R1 expressed in HEK293 cells				Bioorg Med Chem Lett 17: 832-5 (2007) Article DOI: 10.1016/j.bmcl.2006.10.056 BindingDB Entry DOI: 10.7270/Q2GH9HMT
					More data for this Ligand-Target Pair