BDBM50198547 (R)-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)benzylamino)pentan-2-yl)-7-methoxybenzofuran-2-carboxamide::CHEMBL385037

SMILES: COc1cccc2cc(oc12)C(=O)N[C@H](CCCNC(N)=N)C(=O)NCc1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=CJPYBFNPFUDPAW-QGZVFWFLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50198547   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50198547 ((R)-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)ben...) Show SMILES COc1cccc2cc(oc12)C(=O)N[C@H](CCCNC(N)=N)C(=O)NCc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C24H26F3N5O4/c1-35-18-6-2-4-15-12-19(36-20(15)18)22(34)32-17(5-3-11-30-23(28)29)21(33)31-13-14-7-9-16(10-8-14)24(25,26)27/h2,4,6-10,12,17H,3,5,11,13H2,1H3,(H,31,33)(H,32,34)(H4,28,29,30)/t17-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	622	n/a	n/a	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Functional antagonism of MCH-R1 expressed in HEK293 cells				Bioorg Med Chem Lett 17: 832-5 (2007) Article DOI: 10.1016/j.bmcl.2006.10.056 BindingDB Entry DOI: 10.7270/Q2GH9HMT
					More data for this Ligand-Target Pair