BDBM50198558 (R)-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)benzylamino)pentan-2-yl)isoquinoline-3-carboxamide::CHEMBL274326

SMILES: NC(=N)NCCC[C@@H](NC(=O)c1cc2ccccc2cn1)C(=O)NCc1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=KXUKMUPVXLHVKX-LJQANCHMSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50198558   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50198558 ((R)-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)ben...) Show SMILES NC(=N)NCCC[C@@H](NC(=O)c1cc2ccccc2cn1)C(=O)NCc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C24H25F3N6O2/c25-24(26,27)18-9-7-15(8-10-18)13-32-21(34)19(6-3-11-30-23(28)29)33-22(35)20-12-16-4-1-2-5-17(16)14-31-20/h1-2,4-5,7-10,12,14,19H,3,6,11,13H2,(H,32,34)(H,33,35)(H4,28,29,30)/t19-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.81E+3	n/a	n/a	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Functional antagonism of MCH-R1 expressed in HEK293 cells				Bioorg Med Chem Lett 17: 832-5 (2007) Article DOI: 10.1016/j.bmcl.2006.10.056 BindingDB Entry DOI: 10.7270/Q2GH9HMT
					More data for this Ligand-Target Pair