BDBM50198828 4-(5-methyl-7-(3-(methylamino)phenyl)benzo[e][1,2,4]triazin-3-ylamino)-N-(2-(pyrrolidin-1-yl)ethyl)benzenesulfonamide::CHEMBL231627::US8481536, 518

SMILES: CNc1cccc(c1)-c1cc(C)c2nc(Nc3ccc(cc3)S(=O)(=O)NCCN3CCCC3)nnc2c1

InChI Key: InChIKey=QQBZOIWBIDMSHA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50198828   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50198828 (4-(5-methyl-7-(3-(methylamino)phenyl)benzo[e][1,2,...) Show SMILES CNc1cccc(c1)-c1cc(C)c2nc(Nc3ccc(cc3)S(=O)(=O)NCCN3CCCC3)nnc2c1 Show InChI InChI=1S/C27H31N7O2S/c1-19-16-21(20-6-5-7-23(17-20)28-2)18-25-26(19)31-27(33-32-25)30-22-8-10-24(11-9-22)37(35,36)29-12-15-34-13-3-4-14-34/h5-11,16-18,28-29H,3-4,12-15H2,1-2H3,(H,30,31,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	631	n/a	n/a	n/a	n/a	n/a	n/a
TargeGen, Inc. Curated by ChEMBL					Assay Description Inhibition of Src				Bioorg Med Chem Lett 17: 602-8 (2007) Article DOI: 10.1016/j.bmcl.2006.11.006 BindingDB Entry DOI: 10.7270/Q29024MW
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50198828 (4-(5-methyl-7-(3-(methylamino)phenyl)benzo[e][1,2,...) Show SMILES CNc1cccc(c1)-c1cc(C)c2nc(Nc3ccc(cc3)S(=O)(=O)NCCN3CCCC3)nnc2c1 Show InChI InChI=1S/C27H31N7O2S/c1-19-16-21(20-6-5-7-23(17-20)28-2)18-25-26(19)31-27(33-32-25)30-22-8-10-24(11-9-22)37(35,36)29-12-15-34-13-3-4-14-34/h5-11,16-18,28-29H,3-4,12-15H2,1-2H3,(H,30,31,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	631	n/a	n/a	n/a	n/a	n/a	25
TargeGen, Inc. US Patent					Assay Description Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.				US Patent US8481536 (2013) BindingDB Entry DOI: 10.7270/Q2GB22PZ
					More data for this Ligand-Target Pair