BDBM50198875 3-[(2S,4S)-4-(5-bromo-1-indolinyl)-2-pyrrolidinylcarbonyl]-1,3-thiazolidine::CHEMBL223916

SMILES: Brc1ccc2N(CCc2c1)[C@@H]1CN[C@@H](C1)C(=O)N1CCSC1

InChI Key: InChIKey=MFXIKULCYIAANA-KBPBESRZSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50198875   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50198875 (3-[(2S,4S)-4-(5-bromo-1-indolinyl)-2-pyrrolidinylc...) Show SMILES Brc1ccc2N(CCc2c1)[C@@H]1CN[C@@H](C1)C(=O)N1CCSC1 Show InChI InChI=1S/C16H20BrN3OS/c17-12-1-2-15-11(7-12)3-4-20(15)13-8-14(18-9-13)16(21)19-5-6-22-10-19/h1-2,7,13-14,18H,3-6,8-10H2/t13-,14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
Mitsubishi Pharma Corporation Curated by ChEMBL					Assay Description Inhibition of DPP4 in human plasma by fluorescence assay				Bioorg Med Chem 15: 641-55 (2006) Article DOI: 10.1016/j.bmc.2006.10.059 BindingDB Entry DOI: 10.7270/Q21N81X1
					More data for this Ligand-Target Pair
Dipeptidyl peptidase IV (Rattus norvegicus (rat))	BDBM50198875 (3-[(2S,4S)-4-(5-bromo-1-indolinyl)-2-pyrrolidinylc...) Show SMILES Brc1ccc2N(CCc2c1)[C@@H]1CN[C@@H](C1)C(=O)N1CCSC1 Show InChI InChI=1S/C16H20BrN3OS/c17-12-1-2-15-11(7-12)3-4-20(15)13-8-14(18-9-13)16(21)19-5-6-22-10-19/h1-2,7,13-14,18H,3-6,8-10H2/t13-,14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10.7	n/a	n/a	n/a	n/a	n/a	n/a
Mitsubishi Pharma Corporation Curated by ChEMBL					Assay Description Inhibition of DPP4 in rat plasma by fluorescence assay				Bioorg Med Chem 15: 641-55 (2006) Article DOI: 10.1016/j.bmc.2006.10.059 BindingDB Entry DOI: 10.7270/Q21N81X1
					More data for this Ligand-Target Pair