BindingDB PrimarySearch

BDBM50199127 CHEMBL3958215

SMILES: Fc1ccc2C(=O)C(CCN3CCc4ccccc4C3)Cc2c1

InChI Key: InChIKey=QIGRVQBAYKSEIV-UHFFFAOYSA-N

Data: 13 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50199127
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50199127 (CHEMBL3958215) Show SMILES Fc1ccc2C(=O)C(CCN3CCc4ccccc4C3)Cc2c1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Florida A&M University Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT7 receptor by liquid scintillation counting method				Bioorg Med Chem 24: 5730-5740 (2016) Article DOI: 10.1016/j.bmc.2016.09.019 BindingDB Entry DOI: 10.7270/Q2639RQF
Florida A&M University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50199127 (CHEMBL3958215) Show SMILES Fc1ccc2C(=O)C(CCN3CCc4ccccc4C3)Cc2c1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Florida A&M University Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT7 receptor by liquid scintillation counting method				Bioorg Med Chem 24: 5730-5740 (2016) Article DOI: 10.1016/j.bmc.2016.09.019 BindingDB Entry DOI: 10.7270/Q2639RQF
Florida A&M University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50199127 (CHEMBL3958215) Show SMILES Fc1ccc2C(=O)C(CCN3CCc4ccccc4C3)Cc2c1 Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Florida A&M University Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor by liquid scintillation counting method				Bioorg Med Chem 24: 5730-5740 (2016) Article DOI: 10.1016/j.bmc.2016.09.019 BindingDB Entry DOI: 10.7270/Q2639RQF
Florida A&M University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50199127 (CHEMBL3958215) Show SMILES Fc1ccc2C(=O)C(CCN3CCc4ccccc4C3)Cc2c1 Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Florida A&M University Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor by liquid scintillation counting method				Bioorg Med Chem 24: 5730-5740 (2016) Article DOI: 10.1016/j.bmc.2016.09.019 BindingDB Entry DOI: 10.7270/Q2639RQF
Florida A&M University Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50199127 (CHEMBL3958215) Show SMILES Fc1ccc2C(=O)C(CCN3CCc4ccccc4C3)Cc2c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	223	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Florida A&M University Curated by ChEMBL					Assay Description Displacement of [3H]-N-methylspiperone from human dopamine D3 receptor by liquid scintillation counting method				Bioorg Med Chem 24: 5730-5740 (2016) Article DOI: 10.1016/j.bmc.2016.09.019 BindingDB Entry DOI: 10.7270/Q2639RQF
Florida A&M University Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50199127 (CHEMBL3958215) Show SMILES Fc1ccc2C(=O)C(CCN3CCc4ccccc4C3)Cc2c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	224	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Florida A&M University Curated by ChEMBL					Assay Description Displacement of [3H]-N-methylspiperone from human dopamine D3 receptor by liquid scintillation counting method				Bioorg Med Chem 24: 5730-5740 (2016) Article DOI: 10.1016/j.bmc.2016.09.019 BindingDB Entry DOI: 10.7270/Q2639RQF
Florida A&M University Curated by ChEMBL					More data for this Ligand-Target Pair
Dopamine receptor (RAT)	BDBM50199127 (CHEMBL3958215) Show SMILES Fc1ccc2C(=O)C(CCN3CCc4ccccc4C3)Cc2c1 Show InChI	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	251	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Florida A&M University Curated by ChEMBL					Assay Description Displacement of [3H]-N-methylspiperone from rat dopamine D4 receptor by liquid scintillation counting method				Bioorg Med Chem 24: 5730-5740 (2016) Article DOI: 10.1016/j.bmc.2016.09.019 BindingDB Entry DOI: 10.7270/Q2639RQF
Florida A&M University Curated by ChEMBL					More data for this Ligand-Target Pair
Dopamine receptor (RAT)	BDBM50199127 (CHEMBL3958215) Show SMILES Fc1ccc2C(=O)C(CCN3CCc4ccccc4C3)Cc2c1 Show InChI	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	251	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Florida A&M University Curated by ChEMBL					Assay Description Displacement of [3H]-N-methylspiperone from rat dopamine D4 receptor by liquid scintillation counting method				Bioorg Med Chem 24: 5730-5740 (2016) Article DOI: 10.1016/j.bmc.2016.09.019 BindingDB Entry DOI: 10.7270/Q2639RQF
Florida A&M University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50199127 (CHEMBL3958215) Show SMILES Fc1ccc2C(=O)C(CCN3CCc4ccccc4C3)Cc2c1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	294	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Florida A&M University Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT2B receptor by liquid scintillation counting method				Bioorg Med Chem 24: 5730-5740 (2016) Article DOI: 10.1016/j.bmc.2016.09.019 BindingDB Entry DOI: 10.7270/Q2639RQF
Florida A&M University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50199127 (CHEMBL3958215) Show SMILES Fc1ccc2C(=O)C(CCN3CCc4ccccc4C3)Cc2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	750	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Florida A&M University Curated by ChEMBL					Assay Description Displacement of [3H]-N-methylspiperone from human dopamine D2 receptor by liquid scintillation counting method				Bioorg Med Chem 24: 5730-5740 (2016) Article DOI: 10.1016/j.bmc.2016.09.019 BindingDB Entry DOI: 10.7270/Q2639RQF
Florida A&M University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50199127 (CHEMBL3958215) Show SMILES Fc1ccc2C(=O)C(CCN3CCc4ccccc4C3)Cc2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	759	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Florida A&M University Curated by ChEMBL					Assay Description Displacement of [3H]-N-methylspiperone from human dopamine D2 receptor by liquid scintillation counting method				Bioorg Med Chem 24: 5730-5740 (2016) Article DOI: 10.1016/j.bmc.2016.09.019 BindingDB Entry DOI: 10.7270/Q2639RQF
Florida A&M University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50199127 (CHEMBL3958215) Show SMILES Fc1ccc2C(=O)C(CCN3CCc4ccccc4C3)Cc2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Florida A&M University Curated by ChEMBL					Assay Description Displacement of [3H]-ketanserin from human 5-HT2A receptor by liquid scintillation counting method				Bioorg Med Chem 24: 5730-5740 (2016) Article DOI: 10.1016/j.bmc.2016.09.019 BindingDB Entry DOI: 10.7270/Q2639RQF
Florida A&M University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50199127 (CHEMBL3958215) Show SMILES Fc1ccc2C(=O)C(CCN3CCc4ccccc4C3)Cc2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Florida A&M University Curated by ChEMBL					Assay Description Displacement of [3H]-ketanserin from human 5-HT2A receptor by liquid scintillation counting method				Bioorg Med Chem 24: 5730-5740 (2016) Article DOI: 10.1016/j.bmc.2016.09.019 BindingDB Entry DOI: 10.7270/Q2639RQF
Florida A&M University Curated by ChEMBL					More data for this Ligand-Target Pair