BDBM50199207 6-(4-chlorophenyl)-3-[2-(4-morpholinylmethyl)-3,4-dihydro-2H-1,4-benzoxazin-6-yl]thieno[3,2-d]pyrimidin-4-(3H)-one::CHEMBL387085

SMILES: Clc1ccc(cc1)-c1cc2ncn(-c3ccc4OC(CN5CCOCC5)CNc4c3)c(=O)c2s1

InChI Key: InChIKey=YIBPPXKCYWGKQV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50199207   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50199207 (6-(4-chlorophenyl)-3-[2-(4-morpholinylmethyl)-3,4-...) Show SMILES Clc1ccc(cc1)-c1cc2ncn(-c3ccc4OC(CN5CCOCC5)CNc4c3)c(=O)c2s1 Show InChI InChI=1S/C25H23ClN4O3S/c26-17-3-1-16(2-4-17)23-12-21-24(34-23)25(31)30(15-28-21)18-5-6-22-20(11-18)27-13-19(33-22)14-29-7-9-32-10-8-29/h1-6,11-12,15,19,27H,7-10,13-14H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assay				J Med Chem 49: 7095-107 (2006) Article DOI: 10.1021/jm060572f BindingDB Entry DOI: 10.7270/Q2P26XS8
					More data for this Ligand-Target Pair