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SMILES: CCN1CCN(Cc2ccc3cc(ccc3n2)-n2cnc3cc(sc3c2=O)-c2ccc(Cl)cc2)CC1

InChI Key: InChIKey=IPWYSBUTKATQSJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50199211   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50199211
PNG
(6-(4-chlorophenyl)-3-{2-[(4-ethyl-1-piperazinyl)me...)
Show SMILES CCN1CCN(Cc2ccc3cc(ccc3n2)-n2cnc3cc(sc3c2=O)-c2ccc(Cl)cc2)CC1
Show InChI InChI=1S/C28H26ClN5OS/c1-2-32-11-13-33(14-12-32)17-22-8-5-20-15-23(9-10-24(20)31-22)34-18-30-25-16-26(36-27(25)28(34)35)19-3-6-21(29)7-4-19/h3-10,15-16,18H,2,11-14,17H2,1H3
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Article
PubMed
n/an/a 6.20n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assay

J Med Chem 49: 7095-107 (2006)


Article DOI: 10.1021/jm060572f
BindingDB Entry DOI: 10.7270/Q2P26XS8
More data for this
Ligand-Target Pair