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SMILES: CCC(C)c1ccc(cc1)-c1cc2ncn(-c3ccc4nc(CN5CCOCC5)ccc4c3)c(=O)c2s1

InChI Key: InChIKey=DVZUMXKYIYIBCL-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50199213   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50199213
PNG
(6-[4-(1-methylpropyl)phenyl]-3-[2-(4-morpholinylme...)
Show SMILES CCC(C)c1ccc(cc1)-c1cc2ncn(-c3ccc4nc(CN5CCOCC5)ccc4c3)c(=O)c2s1
Show InChI InChI=1S/C30H30N4O2S/c1-3-20(2)21-4-6-22(7-5-21)28-17-27-29(37-28)30(35)34(19-31-27)25-10-11-26-23(16-25)8-9-24(32-26)18-33-12-14-36-15-13-33/h4-11,16-17,19-20H,3,12-15,18H2,1-2H3
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assay

J Med Chem 49: 7095-107 (2006)


Article DOI: 10.1021/jm060572f
BindingDB Entry DOI: 10.7270/Q2P26XS8
More data for this
Ligand-Target Pair