BDBM50199215 6-(4-chlorophenyl)-3-{2-[(4-phenyl-1-piperazinyl)methyl]-6-quinolinyl}thieno[3,2-d]pyrimidin-4(3H)-one::CHEMBL215039

SMILES: Clc1ccc(cc1)-c1cc2ncn(-c3ccc4nc(CN5CCN(CC5)c5ccccc5)ccc4c3)c(=O)c2s1

InChI Key: InChIKey=CSIWZRJTSWJCKM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50199215   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50199215 (6-(4-chlorophenyl)-3-{2-[(4-phenyl-1-piperazinyl)m...) Show SMILES Clc1ccc(cc1)-c1cc2ncn(-c3ccc4nc(CN5CCN(CC5)c5ccccc5)ccc4c3)c(=O)c2s1 Show InChI InChI=1S/C32H26ClN5OS/c33-24-9-6-22(7-10-24)30-19-29-31(40-30)32(39)38(21-34-29)27-12-13-28-23(18-27)8-11-25(35-28)20-36-14-16-37(17-15-36)26-4-2-1-3-5-26/h1-13,18-19,21H,14-17,20H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assay				J Med Chem 49: 7095-107 (2006) Article DOI: 10.1021/jm060572f BindingDB Entry DOI: 10.7270/Q2P26XS8
					More data for this Ligand-Target Pair