BDBM50199220 6-[4-(methyloxy)phenyl]-3-[2-(4-morpholinylmethyl)-6-quinolinyl]thieno[3,2-d]pyrimidin-4(3H)-one::CHEMBL213966

SMILES: COc1ccc(cc1)-c1cc2ncn(-c3ccc4nc(CN5CCOCC5)ccc4c3)c(=O)c2s1

InChI Key: InChIKey=KYMLFJZPYAXAQW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50199220   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50199220 (6-[4-(methyloxy)phenyl]-3-[2-(4-morpholinylmethyl)...) Show SMILES COc1ccc(cc1)-c1cc2ncn(-c3ccc4nc(CN5CCOCC5)ccc4c3)c(=O)c2s1 Show InChI InChI=1S/C27H24N4O3S/c1-33-22-7-3-18(4-8-22)25-15-24-26(35-25)27(32)31(17-28-24)21-6-9-23-19(14-21)2-5-20(29-23)16-30-10-12-34-13-11-30/h2-9,14-15,17H,10-13,16H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assay				J Med Chem 49: 7095-107 (2006) Article DOI: 10.1021/jm060572f BindingDB Entry DOI: 10.7270/Q2P26XS8
					More data for this Ligand-Target Pair