BDBM50199221 6-(4-chlorophenyl)-3-[2-({4-[3-(4-morpholinyl)propyl]-1-piperazinyl}methyl)-6-quinolinyl]thieno[3,2-d]pyrimidin-4(3H)-one::CHEMBL269695

SMILES: Clc1ccc(cc1)-c1cc2ncn(-c3ccc4nc(CN5CCN(CCCN6CCOCC6)CC5)ccc4c3)c(=O)c2s1

InChI Key: InChIKey=CXZNETVGABHSHU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50199221   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50199221 (6-(4-chlorophenyl)-3-[2-({4-[3-(4-morpholinyl)prop...) Show SMILES Clc1ccc(cc1)-c1cc2ncn(-c3ccc4nc(CN5CCN(CCCN6CCOCC6)CC5)ccc4c3)c(=O)c2s1 Show InChI InChI=1S/C33H35ClN6O2S/c34-26-5-2-24(3-6-26)31-21-30-32(43-31)33(41)40(23-35-30)28-8-9-29-25(20-28)4-7-27(36-29)22-39-14-12-37(13-15-39)10-1-11-38-16-18-42-19-17-38/h2-9,20-21,23H,1,10-19,22H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assay				J Med Chem 49: 7095-107 (2006) Article DOI: 10.1021/jm060572f BindingDB Entry DOI: 10.7270/Q2P26XS8
					More data for this Ligand-Target Pair