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SMILES: CN(C)CC1CN(c2cc(ccc2O1)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1)S(=O)(=O)c1ccccc1

InChI Key: InChIKey=AADSFGMHGXEQDC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50199232   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50199232
PNG
(6-(4-chlorophenyl)-3-[2-[(dimethylamino)methyl]-4-...)
Show SMILES CN(C)CC1CN(c2cc(ccc2O1)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C29H25ClN4O4S2/c1-32(2)16-22-17-34(40(36,37)23-6-4-3-5-7-23)25-14-21(12-13-26(25)38-22)33-18-31-24-15-27(39-28(24)29(33)35)19-8-10-20(30)11-9-19/h3-15,18,22H,16-17H2,1-2H3
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Similars
Article
PubMed
n/an/a 6.92E+3n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assay

J Med Chem 49: 7095-107 (2006)


Article DOI: 10.1021/jm060572f
BindingDB Entry DOI: 10.7270/Q2P26XS8
More data for this
Ligand-Target Pair