BDBM50199235 6-(4-chlorophenyl)-3-[2-({4-[4-(trifluoromethyl)phenyl]-1-piperidinyl}methyl)-6-quinolinyl]thieno[3,2-d]pyrimidin-4(3H)-one::CHEMBL214468

SMILES: FC(F)(F)c1ccc(cc1)C1CCN(Cc2ccc3cc(ccc3n2)-n2cnc3cc(sc3c2=O)-c2ccc(Cl)cc2)CC1

InChI Key: InChIKey=GLHXGJYSHGLSID-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50199235   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50199235 (6-(4-chlorophenyl)-3-[2-({4-[4-(trifluoromethyl)ph...) Show SMILES FC(F)(F)c1ccc(cc1)C1CCN(Cc2ccc3cc(ccc3n2)-n2cnc3cc(sc3c2=O)-c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C34H26ClF3N4OS/c35-26-8-3-23(4-9-26)31-18-30-32(44-31)33(43)42(20-39-30)28-11-12-29-24(17-28)5-10-27(40-29)19-41-15-13-22(14-16-41)21-1-6-25(7-2-21)34(36,37)38/h1-12,17-18,20,22H,13-16,19H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assay				J Med Chem 49: 7095-107 (2006) Article DOI: 10.1021/jm060572f BindingDB Entry DOI: 10.7270/Q2P26XS8
					More data for this Ligand-Target Pair