BDBM50199265 6-(4-chlorophenyl)-3-(2-{[(2R)-2-(methoxymethyl)pyrrolidin-1-yl]methyl}-1-methyl-1H-indol-5-yl)thieno[3,2-d]pyrimidin-4(3H)-one::CHEMBL217733

SMILES: COC[C@H]1CCCN1Cc1cc2cc(ccc2n1C)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1

InChI Key: InChIKey=JNHZMEBIKUJAIN-JOCHJYFZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50199265   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50199265 (6-(4-chlorophenyl)-3-(2-{[(2R)-2-(methoxymethyl)py...) Show SMILES COC[C@H]1CCCN1Cc1cc2cc(ccc2n1C)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C28H27ClN4O2S/c1-31-23(15-32-11-3-4-22(32)16-35-2)13-19-12-21(9-10-25(19)31)33-17-30-24-14-26(36-27(24)28(33)34)18-5-7-20(29)8-6-18/h5-10,12-14,17,22H,3-4,11,15-16H2,1-2H3/t22-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assay				J Med Chem 49: 7108-18 (2006) Article DOI: 10.1021/jm060814b BindingDB Entry DOI: 10.7270/Q2JD4WFT
					More data for this Ligand-Target Pair