BDBM50199496 3-(1-(1-((1r,4r)-4-tert-butylcyclohexyl)-3-(3,5-dichlorophenyl)ureido)-2,3-dihydro-1H-indene-5-carboxamido)propanoic acid::CHEMBL430163

SMILES: CC(C)(C)[C@H]1CC[C@@H](CC1)N(C1CCc2cc(ccc12)C(=O)NCCC(O)=O)C(=O)Nc1cc(Cl)cc(Cl)c1

InChI Key: InChIKey=GZGAUBCVTUVGJU-SUMMSQPPSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50199496   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon receptor (Homo sapiens (Human))	BDBM50199496 (3-(1-(1-((1r,4r)-4-tert-butylcyclohexyl)-3-(3,5-di...) Show SMILES CC(C)(C)[C@H]1CC[C@@H](CC1)N(C1CCc2cc(ccc12)C(=O)NCCC(O)=O)C(=O)Nc1cc(Cl)cc(Cl)c1 |w:11.11,wU:7.10,wD:4.3,(-2.67,-6.08,;-2.66,-4.55,;-1.12,-4.56,;-4.2,-4.55,;-2.66,-3.01,;-1.32,-2.24,;-1.31,-.69,;-2.64,.07,;-3.98,-.7,;-3.99,-2.23,;-2.64,1.61,;-1.3,2.38,;-.99,3.88,;.88,3.84,;1.35,2.39,;2.68,1.62,;2.69,.08,;1.36,-.69,;.02,.07,;.03,1.61,;4.03,-.69,;4.03,-2.23,;5.36,.08,;6.69,-.68,;8.02,.09,;9.36,-.68,;10.69,.1,;9.36,-2.22,;-3.97,2.38,;-3.97,3.92,;-5.31,1.61,;-6.64,2.37,;-6.65,3.93,;-7.99,4.69,;-7.99,6.23,;-9.31,3.92,;-9.31,2.37,;-10.65,1.61,;-7.98,1.6,)| Show InChI InChI=1S/C30H37Cl2N3O4/c1-30(2,3)20-6-8-24(9-7-20)35(29(39)34-23-16-21(31)15-22(32)17-23)26-11-5-18-14-19(4-10-25(18)26)28(38)33-13-12-27(36)37/h4,10,14-17,20,24,26H,5-9,11-13H2,1-3H3,(H,33,38)(H,34,39)(H,36,37)/t20-,24-,26?	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125]glucagon from human glucagon receptor expressed in CHO cells				Bioorg Med Chem Lett 17: 587-92 (2007) Article DOI: 10.1016/j.bmcl.2006.11.014 BindingDB Entry DOI: 10.7270/Q2N58M0Q
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50199496 (3-(1-(1-((1r,4r)-4-tert-butylcyclohexyl)-3-(3,5-di...) Show SMILES CC(C)(C)[C@H]1CC[C@@H](CC1)N(C1CCc2cc(ccc12)C(=O)NCCC(O)=O)C(=O)Nc1cc(Cl)cc(Cl)c1 |w:11.11,wU:7.10,wD:4.3,(-2.67,-6.08,;-2.66,-4.55,;-1.12,-4.56,;-4.2,-4.55,;-2.66,-3.01,;-1.32,-2.24,;-1.31,-.69,;-2.64,.07,;-3.98,-.7,;-3.99,-2.23,;-2.64,1.61,;-1.3,2.38,;-.99,3.88,;.88,3.84,;1.35,2.39,;2.68,1.62,;2.69,.08,;1.36,-.69,;.02,.07,;.03,1.61,;4.03,-.69,;4.03,-2.23,;5.36,.08,;6.69,-.68,;8.02,.09,;9.36,-.68,;10.69,.1,;9.36,-2.22,;-3.97,2.38,;-3.97,3.92,;-5.31,1.61,;-6.64,2.37,;-6.65,3.93,;-7.99,4.69,;-7.99,6.23,;-9.31,3.92,;-9.31,2.37,;-10.65,1.61,;-7.98,1.6,)| Show InChI InChI=1S/C30H37Cl2N3O4/c1-30(2,3)20-6-8-24(9-7-20)35(29(39)34-23-16-21(31)15-22(32)17-23)26-11-5-18-14-19(4-10-25(18)26)28(38)33-13-12-27(36)37/h4,10,14-17,20,24,26H,5-9,11-13H2,1-3H3,(H,33,38)(H,34,39)(H,36,37)/t20-,24-,26?	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human glucagon receptor transfected in CHO cells assessed as inhibition of glucagon-induced cAMP accumulation				Bioorg Med Chem Lett 17: 587-92 (2007) Article DOI: 10.1016/j.bmcl.2006.11.014 BindingDB Entry DOI: 10.7270/Q2N58M0Q
					More data for this Ligand-Target Pair
Gastric inhibitory polypeptide receptor (Homo sapiens (Human))	BDBM50199496 (3-(1-(1-((1r,4r)-4-tert-butylcyclohexyl)-3-(3,5-di...) Show SMILES CC(C)(C)[C@H]1CC[C@@H](CC1)N(C1CCc2cc(ccc12)C(=O)NCCC(O)=O)C(=O)Nc1cc(Cl)cc(Cl)c1 |w:11.11,wU:7.10,wD:4.3,(-2.67,-6.08,;-2.66,-4.55,;-1.12,-4.56,;-4.2,-4.55,;-2.66,-3.01,;-1.32,-2.24,;-1.31,-.69,;-2.64,.07,;-3.98,-.7,;-3.99,-2.23,;-2.64,1.61,;-1.3,2.38,;-.99,3.88,;.88,3.84,;1.35,2.39,;2.68,1.62,;2.69,.08,;1.36,-.69,;.02,.07,;.03,1.61,;4.03,-.69,;4.03,-2.23,;5.36,.08,;6.69,-.68,;8.02,.09,;9.36,-.68,;10.69,.1,;9.36,-2.22,;-3.97,2.38,;-3.97,3.92,;-5.31,1.61,;-6.64,2.37,;-6.65,3.93,;-7.99,4.69,;-7.99,6.23,;-9.31,3.92,;-9.31,2.37,;-10.65,1.61,;-7.98,1.6,)| Show InChI InChI=1S/C30H37Cl2N3O4/c1-30(2,3)20-6-8-24(9-7-20)35(29(39)34-23-16-21(31)15-22(32)17-23)26-11-5-18-14-19(4-10-25(18)26)28(38)33-13-12-27(36)37/h4,10,14-17,20,24,26H,5-9,11-13H2,1-3H3,(H,33,38)(H,34,39)(H,36,37)/t20-,24-,26?	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human GIP receptor transfected in CHO cells assessed as inhibition of glucagon-induced cAMP accumulation				Bioorg Med Chem Lett 17: 587-92 (2007) Article DOI: 10.1016/j.bmcl.2006.11.014 BindingDB Entry DOI: 10.7270/Q2N58M0Q
					More data for this Ligand-Target Pair