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SMILES: Nc1nccn2c(nc(-c3cccc(OCc4ccc(F)c(F)c4)c3)c12)C1CCC1

InChI Key: InChIKey=FIBLFKBOXDHFCC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50199633   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Insulin-like growth factor 1 receptor


(Homo sapiens (Human))		BDBM50199633
PNG
(1-(3-(3,4-difluorobenzyloxy)phenyl)-3-cyclobutylim...)
Show SMILES Nc1nccn2c(nc(-c3cccc(OCc4ccc(F)c(F)c4)c3)c12)C1CCC1
Show InChI InChI=1S/C23H20F2N4O/c24-18-8-7-14(11-19(18)25)13-30-17-6-2-5-16(12-17)20-21-22(26)27-9-10-29(21)23(28-20)15-3-1-4-15/h2,5-12,15H,1,3-4,13H2,(H2,26,27)
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MMDB

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Article
PubMed
n/an/a 4.48E+3n/an/an/an/an/an/a



OSI Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant GST-IGF1R activity

Bioorg Med Chem Lett 17: 1091-7 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.016
BindingDB Entry DOI: 10.7270/Q2QZ29MB
More data for this
Ligand-Target Pair