BDBM50199886 CHEMBL3939491

SMILES: COc1ccc(cc1S(=O)(=O)NC1CC1)-c1c(C)nc2c(NCCNC(C)=O)cc(Cl)nn12

InChI Key: InChIKey=FUQRQRGDRIZZRI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50199886   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50199886 (CHEMBL3939491) Show SMILES COc1ccc(cc1S(=O)(=O)NC1CC1)-c1c(C)nc2c(NCCNC(C)=O)cc(Cl)nn12 Show InChI InChI=1S/C21H25ClN6O4S/c1-12-20(14-4-7-17(32-3)18(10-14)33(30,31)27-15-5-6-15)28-21(25-12)16(11-19(22)26-28)24-9-8-23-13(2)29/h4,7,10-11,15,24,27H,5-6,8-9H2,1-3H3,(H,23,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	106	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of PI4KB (unknown origin) by ADP-Glo kinase assay				J Med Chem 60: 100-118 (2017) Article DOI: 10.1021/acs.jmedchem.6b01465 BindingDB Entry DOI: 10.7270/Q28054K8
					More data for this Ligand-Target Pair