BDBM50200448 4-sulfamoyl-N-[1-((2S,3S,4R,5R)-3,4,5-trihydroxy-tetrahydro-pyran-2-yl)-1H-[1,2,3]triazol-4-ylmethyl]-benzamide::CHEMBL231896
SMILES: NS(=O)(=O)c1ccc(cc1)C(=O)NCc1cn(nn1)[C@H]1OC[C@@H](O)[C@@H](O)[C@@H]1O
InChI Key: InChIKey=FBBVGKUOXFKGAI-CXTNEJHOSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carbonic anhydrase 12 (Homo sapiens (Human)) | BDBM50200448 (4-sulfamoyl-N-[1-((2S,3S,4R,5R)-3,4,5-trihydroxy-t...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 11.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University Curated by ChEMBL | Assay Description Inhibition of human recombinant CA12 by CO2 hydration assay | Bioorg Med Chem Lett 17: 987-92 (2007) Article DOI: 10.1016/j.bmcl.2006.11.046 BindingDB Entry DOI: 10.7270/Q2JD4XMG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 14 (Homo sapiens (Human)) | BDBM50200448 (4-sulfamoyl-N-[1-((2S,3S,4R,5R)-3,4,5-trihydroxy-t...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 101 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University Curated by ChEMBL | Assay Description Inhibition of human recombinant CA14 by CO2 hydration assay | Bioorg Med Chem Lett 17: 987-92 (2007) Article DOI: 10.1016/j.bmcl.2006.11.046 BindingDB Entry DOI: 10.7270/Q2JD4XMG | |||||||||||
More data for this Ligand-Target Pair |