null

SMILES: CN(C)[C@@H]1CCN(CCc2ccc3cc(ccc3c2)-c2ccc(cc2)C#N)C1

InChI Key: InChIKey=OSFQTGQOBLQGDK-RUZDIDTESA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50200630   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50200630 ((R)-4-(6-(2-(3-(dimethylamino)pyrrolidin-1-yl)ethy...) Show SMILES CN(C)[C@@H]1CCN(CCc2ccc3cc(ccc3c2)-c2ccc(cc2)C#N)C1 Show InChI InChI=1S/C25H27N3/c1-27(2)25-12-14-28(18-25)13-11-19-3-8-24-16-23(10-9-22(24)15-19)21-6-4-20(17-26)5-7-21/h3-10,15-16,25H,11-14,18H2,1-2H3/t25-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 17: 1443-6 (2007) Article DOI: 10.1016/j.bmcl.2006.11.073 BindingDB Entry DOI: 10.7270/Q2416WR3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50200630 ((R)-4-(6-(2-(3-(dimethylamino)pyrrolidin-1-yl)ethy...) Show SMILES CN(C)[C@@H]1CCN(CCc2ccc3cc(ccc3c2)-c2ccc(cc2)C#N)C1 Show InChI InChI=1S/C25H27N3/c1-27(2)25-12-14-28(18-25)13-11-19-3-8-24-16-23(10-9-22(24)15-19)21-6-4-20(17-26)5-7-21/h3-10,15-16,25H,11-14,18H2,1-2H3/t25-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methylhistamine from histamine H3 receptor in rat cortical membranes				Bioorg Med Chem Lett 17: 1443-6 (2007) Article DOI: 10.1016/j.bmcl.2006.11.073 BindingDB Entry DOI: 10.7270/Q2416WR3
					More data for this Ligand-Target Pair