BDBM50200644 4-(6-(2-(pyrrolidin-1-yl)ethyl)naphthalen-2-yl)benzonitrile::CHEMBL247702

SMILES: N#Cc1ccc(cc1)-c1ccc2cc(CCN3CCCC3)ccc2c1

InChI Key: InChIKey=LOTXDFZYMSSJRX-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50200644   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50200644 (4-(6-(2-(pyrrolidin-1-yl)ethyl)naphthalen-2-yl)ben...) Show SMILES N#Cc1ccc(cc1)-c1ccc2cc(CCN3CCCC3)ccc2c1 Show InChI InChI=1S/C23H22N2/c24-17-19-4-6-20(7-5-19)22-10-9-21-15-18(3-8-23(21)16-22)11-14-25-12-1-2-13-25/h3-10,15-16H,1-2,11-14H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.490	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 17: 1443-6 (2007) Article DOI: 10.1016/j.bmcl.2006.11.073 BindingDB Entry DOI: 10.7270/Q2416WR3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50200644 (4-(6-(2-(pyrrolidin-1-yl)ethyl)naphthalen-2-yl)ben...) Show SMILES N#Cc1ccc(cc1)-c1ccc2cc(CCN3CCCC3)ccc2c1 Show InChI InChI=1S/C23H22N2/c24-17-19-4-6-20(7-5-19)22-10-9-21-15-18(3-8-23(21)16-22)11-14-25-12-1-2-13-25/h3-10,15-16H,1-2,11-14H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methylhistamine from histamine H3 receptor in rat cortical membranes				Bioorg Med Chem Lett 17: 1443-6 (2007) Article DOI: 10.1016/j.bmcl.2006.11.073 BindingDB Entry DOI: 10.7270/Q2416WR3
					More data for this Ligand-Target Pair