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SMILES: Clc1ccc(cc1)-c1nn[nH]c1C#N

InChI Key: InChIKey=KBDVIKMDRWVMPM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50200758   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Receptor tyrosine-protein kinase erbB-2


(Homo sapiens (Human))		BDBM50200758
PNG
(4-(4-chlorophenyl)-5-cyano-2H-1,2,3-triazole | CHE...)
Show SMILES Clc1ccc(cc1)-c1nn[nH]c1C#N
Show InChI InChI=1S/C9H5ClN4/c10-7-3-1-6(2-4-7)9-8(5-11)12-14-13-9/h1-4H,(H,12,13,14)
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Article
PubMed
n/an/a 1.10E+4n/an/an/an/an/an/a



Sun Yat-sen University

Curated by ChEMBL


Assay Description
Inhibition of HER2 tyrosine kinase phosphorylation in human MDA-MB-453 cells by Western blot assay

Bioorg Med Chem 15: 1533-8 (2007)


Article DOI: 10.1016/j.bmc.2006.09.041
BindingDB Entry DOI: 10.7270/Q2M0452P
More data for this
Ligand-Target Pair