BDBM50201108 2-[(trans-2,6-dimethylmorpholin-4-yl)methyl]-1,1,1-trifluoro-4-(5-fluoro-2-methoxyphenyl)-4-methylpentan-2-ol::CHEMBL218830

SMILES: COc1ccc(F)cc1C(C)(C)CC(O)(CN1C[C@H](C)O[C@@H](C)C1)C(F)(F)F

InChI Key: InChIKey=YRAUBPBLFNFPPH-QKBJIULESA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50201108   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50201108 (2-[(trans-2,6-dimethylmorpholin-4-yl)methyl]-1,1,1...) Show SMILES COc1ccc(F)cc1C(C)(C)CC(O)(CN1C[C@H](C)O[C@@H](C)C1)C(F)(F)F |r| Show InChI InChI=1S/C20H29F4NO3/c1-13-9-25(10-14(2)28-13)12-19(26,20(22,23)24)11-18(3,4)16-8-15(21)6-7-17(16)27-5/h6-8,13-14,26H,9-12H2,1-5H3/t13-,14-,19?/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of tetramethylrhodamine labeled dexamethosone binding to MR by FP assay				J Med Chem 49: 7887-96 (2006) Article DOI: 10.1021/jm061273t BindingDB Entry DOI: 10.7270/Q2BG2PTB
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50201108 (2-[(trans-2,6-dimethylmorpholin-4-yl)methyl]-1,1,1...) Show SMILES COc1ccc(F)cc1C(C)(C)CC(O)(CN1C[C@H](C)O[C@@H](C)C1)C(F)(F)F |r| Show InChI InChI=1S/C20H29F4NO3/c1-13-9-25(10-14(2)28-13)12-19(26,20(22,23)24)11-18(3,4)16-8-15(21)6-7-17(16)27-5/h6-8,13-14,26H,9-12H2,1-5H3/t13-,14-,19?/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of tetramethylrhodamine labeled RU486 binding to PR by FP assay				J Med Chem 49: 7887-96 (2006) Article DOI: 10.1021/jm061273t BindingDB Entry DOI: 10.7270/Q2BG2PTB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50201108 (2-[(trans-2,6-dimethylmorpholin-4-yl)methyl]-1,1,1...) Show SMILES COc1ccc(F)cc1C(C)(C)CC(O)(CN1C[C@H](C)O[C@@H](C)C1)C(F)(F)F |r| Show InChI InChI=1S/C20H29F4NO3/c1-13-9-25(10-14(2)28-13)12-19(26,20(22,23)24)11-18(3,4)16-8-15(21)6-7-17(16)27-5/h6-8,13-14,26H,9-12H2,1-5H3/t13-,14-,19?/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of tetramethylrhodamine labeled dexamethosone binding to GR by FP assay				J Med Chem 49: 7887-96 (2006) Article DOI: 10.1021/jm061273t BindingDB Entry DOI: 10.7270/Q2BG2PTB
					More data for this Ligand-Target Pair