BDBM50201138 3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidazol-2-yl)-4-(2-(3-chloro-4-fluorophenyl)-2-hydroxyethylamino)pyridin-2(1H)-one::CHEMBL231212

SMILES: Cc1cc(cc2nc([nH]c12)-c1c(NCC(O)c2ccc(F)c(Cl)c2)cc[nH]c1=O)-n1ccnc1

InChI Key: InChIKey=DJEARTUSVWKEAS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50201138   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin-like growth factor I receptor (Homo sapiens (Human))	BDBM50201138 (3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...) Show SMILES Cc1cc(cc2nc([nH]c12)-c1c(NCC(O)c2ccc(F)c(Cl)c2)cc[nH]c1=O)-n1ccnc1 Show InChI InChI=1S/C24H20ClFN6O2/c1-13-8-15(32-7-6-27-12-32)10-19-22(13)31-23(30-19)21-18(4-5-28-24(21)34)29-11-20(33)14-2-3-17(26)16(25)9-14/h2-10,12,20,33H,11H2,1H3,(H,30,31)(H2,28,29,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of IGF1R				Bioorg Med Chem Lett 17: 974-7 (2007) Article DOI: 10.1016/j.bmcl.2006.11.041 BindingDB Entry DOI: 10.7270/Q25T3K4D
					More data for this Ligand-Target Pair
Insulin-like growth factor I receptor (Homo sapiens (Human))	BDBM50201138 (3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...) Show SMILES Cc1cc(cc2nc([nH]c12)-c1c(NCC(O)c2ccc(F)c(Cl)c2)cc[nH]c1=O)-n1ccnc1 Show InChI InChI=1S/C24H20ClFN6O2/c1-13-8-15(32-7-6-27-12-32)10-19-22(13)31-23(30-19)21-18(4-5-28-24(21)34)29-11-20(33)14-2-3-17(26)16(25)9-14/h2-10,12,20,33H,11H2,1H3,(H,30,31)(H2,28,29,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	760	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of IGF1R expressed in Sal cells				Bioorg Med Chem Lett 17: 974-7 (2007) Article DOI: 10.1016/j.bmcl.2006.11.041 BindingDB Entry DOI: 10.7270/Q25T3K4D
					More data for this Ligand-Target Pair