BDBM50201175 CHEMBL3961508

SMILES: CN1CCN(Cc2ccc(cc2)-c2cn3CCCC[C@H](N)C(=O)NCCCCNc4ncc2c3n4)CC1

InChI Key: InChIKey=UENPHVZMJZONSS-VWLOTQADSA-N

Data: 4 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50201175   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50201175 (CHEMBL3961508) Show SMILES CN1CCN(Cc2ccc(cc2)-c2cn3CCCC[C@H](N)C(=O)NCCCCNc4ncc2c3n4)CC1 |r| Show InChI InChI=1S/C28H40N8O/c1-34-14-16-35(17-15-34)19-21-7-9-22(10-8-21)24-20-36-13-5-2-6-25(29)27(37)30-11-3-4-12-31-28-32-18-23(24)26(36)33-28/h7-10,18,20,25H,2-6,11-17,19,29H2,1H3,(H,30,37)(H,31,32,33)/t25-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Flt3 (unknown origin) by microfluidic capillary electrophoresis assay				ACS Med Chem Lett 7: 1044-1049 (2016) Article DOI: 10.1021/acsmedchemlett.6b00221 BindingDB Entry DOI: 10.7270/Q208679K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM50201175 (CHEMBL3961508) Show SMILES CN1CCN(Cc2ccc(cc2)-c2cn3CCCC[C@H](N)C(=O)NCCCCNc4ncc2c3n4)CC1 |r| Show InChI InChI=1S/C28H40N8O/c1-34-14-16-35(17-15-34)19-21-7-9-22(10-8-21)24-20-36-13-5-2-6-25(29)27(37)30-11-3-4-12-31-28-32-18-23(24)26(36)33-28/h7-10,18,20,25H,2-6,11-17,19,29H2,1H3,(H,30,37)(H,31,32,33)/t25-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Axl (unknown origin) by microfluidic capillary electrophoresis assay				ACS Med Chem Lett 7: 1044-1049 (2016) Article DOI: 10.1021/acsmedchemlett.6b00221 BindingDB Entry DOI: 10.7270/Q208679K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM50201175 (CHEMBL3961508) Show SMILES CN1CCN(Cc2ccc(cc2)-c2cn3CCCC[C@H](N)C(=O)NCCCCNc4ncc2c3n4)CC1 |r| Show InChI InChI=1S/C28H40N8O/c1-34-14-16-35(17-15-34)19-21-7-9-22(10-8-21)24-20-36-13-5-2-6-25(29)27(37)30-11-3-4-12-31-28-32-18-23(24)26(36)33-28/h7-10,18,20,25H,2-6,11-17,19,29H2,1H3,(H,30,37)(H,31,32,33)/t25-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Tyro3 (unknown origin) by microfluidic capillary electrophoresis assay				ACS Med Chem Lett 7: 1044-1049 (2016) Article DOI: 10.1021/acsmedchemlett.6b00221 BindingDB Entry DOI: 10.7270/Q208679K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50201175 (CHEMBL3961508) Show SMILES CN1CCN(Cc2ccc(cc2)-c2cn3CCCC[C@H](N)C(=O)NCCCCNc4ncc2c3n4)CC1 |r| Show InChI InChI=1S/C28H40N8O/c1-34-14-16-35(17-15-34)19-21-7-9-22(10-8-21)24-20-36-13-5-2-6-25(29)27(37)30-11-3-4-12-31-28-32-18-23(24)26(36)33-28/h7-10,18,20,25H,2-6,11-17,19,29H2,1H3,(H,30,37)(H,31,32,33)/t25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of human MerTK kinase domain (1585 to 3000 residues) expressed in HEK293 cells co-expressing rat EGFR LBD assessed as inhibition of EGF-st...				ACS Med Chem Lett 7: 1044-1049 (2016) Article DOI: 10.1021/acsmedchemlett.6b00221 BindingDB Entry DOI: 10.7270/Q208679K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50201175 (CHEMBL3961508) Show SMILES CN1CCN(Cc2ccc(cc2)-c2cn3CCCC[C@H](N)C(=O)NCCCCNc4ncc2c3n4)CC1 |r| Show InChI InChI=1S/C28H40N8O/c1-34-14-16-35(17-15-34)19-21-7-9-22(10-8-21)24-20-36-13-5-2-6-25(29)27(37)30-11-3-4-12-31-28-32-18-23(24)26(36)33-28/h7-10,18,20,25H,2-6,11-17,19,29H2,1H3,(H,30,37)(H,31,32,33)/t25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.90	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of MerTK (unknown origin) by microfluidic capillary electrophoresis assay				ACS Med Chem Lett 7: 1044-1049 (2016) Article DOI: 10.1021/acsmedchemlett.6b00221 BindingDB Entry DOI: 10.7270/Q208679K
					More data for this Ligand-Target Pair