null

SMILES: Cn1cnc(NCc2ccncc2)c1C(=O)Nc1ccc(c(Cl)c1)C(F)(F)F

InChI Key: InChIKey=MNCGWHHPXZQUQI-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50201354   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201354 (CHEMBL394020 | N-(3-chloro-4-(trifluoromethyl)phen...) Show SMILES Cn1cnc(NCc2ccncc2)c1C(=O)Nc1ccc(c(Cl)c1)C(F)(F)F Show InChI InChI=1S/C18H15ClF3N5O/c1-27-10-25-16(24-9-11-4-6-23-7-5-11)15(27)17(28)26-12-2-3-13(14(19)8-12)18(20,21)22/h2-8,10,24H,9H2,1H3,(H,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR2 by HTRF assay				Bioorg Med Chem Lett 17: 1369-75 (2007) Article DOI: 10.1016/j.bmcl.2006.11.087 BindingDB Entry DOI: 10.7270/Q2125S92
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50201354 (CHEMBL394020 | N-(3-chloro-4-(trifluoromethyl)phen...) Show SMILES Cn1cnc(NCc2ccncc2)c1C(=O)Nc1ccc(c(Cl)c1)C(F)(F)F Show InChI InChI=1S/C18H15ClF3N5O/c1-27-10-25-16(24-9-11-4-6-23-7-5-11)15(27)17(28)26-12-2-3-13(14(19)8-12)18(20,21)22/h2-8,10,24H,9H2,1H3,(H,26,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR1 by HTRF assay				Bioorg Med Chem Lett 17: 1369-75 (2007) Article DOI: 10.1016/j.bmcl.2006.11.087 BindingDB Entry DOI: 10.7270/Q2125S92
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201354 (CHEMBL394020 | N-(3-chloro-4-(trifluoromethyl)phen...) Show SMILES Cn1cnc(NCc2ccncc2)c1C(=O)Nc1ccc(c(Cl)c1)C(F)(F)F Show InChI InChI=1S/C18H15ClF3N5O/c1-27-10-25-16(24-9-11-4-6-23-7-5-11)15(27)17(28)26-12-2-3-13(14(19)8-12)18(20,21)22/h2-8,10,24H,9H2,1H3,(H,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR2 by cell-based assay				Bioorg Med Chem Lett 17: 1369-75 (2007) Article DOI: 10.1016/j.bmcl.2006.11.087 BindingDB Entry DOI: 10.7270/Q2125S92
					More data for this Ligand-Target Pair