null

SMILES: Cc1cc(NC(=O)c2c(NCc3ccncc3)cnn2C)ccc1C(F)(F)F

InChI Key: InChIKey=YSSBFDUPJYHIMF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50201382   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201382 (1-methyl-N-(3-methyl-4-(trifluoromethyl)phenyl)-4-...) Show SMILES Cc1cc(NC(=O)c2c(NCc3ccncc3)cnn2C)ccc1C(F)(F)F Show InChI InChI=1S/C19H18F3N5O/c1-12-9-14(3-4-15(12)19(20,21)22)26-18(28)17-16(11-25-27(17)2)24-10-13-5-7-23-8-6-13/h3-9,11,24H,10H2,1-2H3,(H,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR2 by HTRF assay				Bioorg Med Chem Lett 17: 1369-75 (2007) Article DOI: 10.1016/j.bmcl.2006.11.087 BindingDB Entry DOI: 10.7270/Q2125S92
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201382 (1-methyl-N-(3-methyl-4-(trifluoromethyl)phenyl)-4-...) Show SMILES Cc1cc(NC(=O)c2c(NCc3ccncc3)cnn2C)ccc1C(F)(F)F Show InChI InChI=1S/C19H18F3N5O/c1-12-9-14(3-4-15(12)19(20,21)22)26-18(28)17-16(11-25-27(17)2)24-10-13-5-7-23-8-6-13/h3-9,11,24H,10H2,1-2H3,(H,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR2 by cell-based assay				Bioorg Med Chem Lett 17: 1369-75 (2007) Article DOI: 10.1016/j.bmcl.2006.11.087 BindingDB Entry DOI: 10.7270/Q2125S92
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50201382 (1-methyl-N-(3-methyl-4-(trifluoromethyl)phenyl)-4-...) Show SMILES Cc1cc(NC(=O)c2c(NCc3ccncc3)cnn2C)ccc1C(F)(F)F Show InChI InChI=1S/C19H18F3N5O/c1-12-9-14(3-4-15(12)19(20,21)22)26-18(28)17-16(11-25-27(17)2)24-10-13-5-7-23-8-6-13/h3-9,11,24H,10H2,1-2H3,(H,26,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR1 by HTRF assay				Bioorg Med Chem Lett 17: 1369-75 (2007) Article DOI: 10.1016/j.bmcl.2006.11.087 BindingDB Entry DOI: 10.7270/Q2125S92
					More data for this Ligand-Target Pair