null

SMILES: CC(C)c1ccc(NC(=O)c2c(NCc3ccncc3)ncn2C)cc1

InChI Key: InChIKey=CEDYKRBCAXLBBQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50201400   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201400 (CHEMBL238522 | N-(4-isopropylphenyl)-1-methyl-4-(p...) Show SMILES CC(C)c1ccc(NC(=O)c2c(NCc3ccncc3)ncn2C)cc1 Show InChI InChI=1S/C20H23N5O/c1-14(2)16-4-6-17(7-5-16)24-20(26)18-19(23-13-25(18)3)22-12-15-8-10-21-11-9-15/h4-11,13-14,22H,12H2,1-3H3,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR2 by cell-based assay				Bioorg Med Chem Lett 17: 1369-75 (2007) Article DOI: 10.1016/j.bmcl.2006.11.087 BindingDB Entry DOI: 10.7270/Q2125S92
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201400 (CHEMBL238522 | N-(4-isopropylphenyl)-1-methyl-4-(p...) Show SMILES CC(C)c1ccc(NC(=O)c2c(NCc3ccncc3)ncn2C)cc1 Show InChI InChI=1S/C20H23N5O/c1-14(2)16-4-6-17(7-5-16)24-20(26)18-19(23-13-25(18)3)22-12-15-8-10-21-11-9-15/h4-11,13-14,22H,12H2,1-3H3,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR2 by HTRF assay				Bioorg Med Chem Lett 17: 1369-75 (2007) Article DOI: 10.1016/j.bmcl.2006.11.087 BindingDB Entry DOI: 10.7270/Q2125S92
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50201400 (CHEMBL238522 | N-(4-isopropylphenyl)-1-methyl-4-(p...) Show SMILES CC(C)c1ccc(NC(=O)c2c(NCc3ccncc3)ncn2C)cc1 Show InChI InChI=1S/C20H23N5O/c1-14(2)16-4-6-17(7-5-16)24-20(26)18-19(23-13-25(18)3)22-12-15-8-10-21-11-9-15/h4-11,13-14,22H,12H2,1-3H3,(H,24,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR1 by HTRF assay				Bioorg Med Chem Lett 17: 1369-75 (2007) Article DOI: 10.1016/j.bmcl.2006.11.087 BindingDB Entry DOI: 10.7270/Q2125S92
					More data for this Ligand-Target Pair