null

SMILES: Cc1cccc(NC(=O)c2cccc3oc(=O)[nH]c23)n1

InChI Key: InChIKey=BHEYXHBTVHTOAL-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50201484   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50201484 (CHEMBL396691 | N-(6-methylpyridin-2-yl)-2-oxo-2,3-...) Show SMILES Cc1cccc(NC(=O)c2cccc3oc(=O)[nH]c23)n1 Show InChI InChI=1S/C14H11N3O3/c1-8-4-2-7-11(15-8)16-13(18)9-5-3-6-10-12(9)17-14(19)20-10/h2-7H,1H3,(H,17,19)(H,15,16,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	95	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Binding affinity to mGluR5				Bioorg Med Chem Lett 17: 1302-6 (2007) Article DOI: 10.1016/j.bmcl.2006.12.006 BindingDB Entry DOI: 10.7270/Q2H41R3G
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50201484 (CHEMBL396691 | N-(6-methylpyridin-2-yl)-2-oxo-2,3-...) Show SMILES Cc1cccc(NC(=O)c2cccc3oc(=O)[nH]c23)n1 Show InChI InChI=1S/C14H11N3O3/c1-8-4-2-7-11(15-8)16-13(18)9-5-3-6-10-12(9)17-14(19)20-10/h2-7H,1H3,(H,17,19)(H,15,16,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Antagonist activity at mGluR5 assessed as inhibition of Ca2+ efflux by FLIPR				Bioorg Med Chem Lett 17: 1302-6 (2007) Article DOI: 10.1016/j.bmcl.2006.12.006 BindingDB Entry DOI: 10.7270/Q2H41R3G
					More data for this Ligand-Target Pair