BDBM50201502 2-(3H-imidazo[4,5-c]pyridin-3-yl)-7-methyl-N-(3-morpholinopropyl)-4-((S)-1-phenylethylamino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide::CHEMBL233969

SMILES: C[C@H](Nc1nc(nc2n(C)c(cc12)C(=O)NCCCN1CCOCC1)-n1cnc2ccncc12)c1ccccc1

InChI Key: InChIKey=MXWHTSIBOUKPHF-FQEVSTJZSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50201502   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50201502 (2-(3H-imidazo[4,5-c]pyridin-3-yl)-7-methyl-N-(3-mo...) Show SMILES C[C@H](Nc1nc(nc2n(C)c(cc12)C(=O)NCCCN1CCOCC1)-n1cnc2ccncc12)c1ccccc1 Show InChI InChI=1S/C29H33N9O2/c1-20(21-7-4-3-5-8-21)33-26-22-17-24(28(39)31-10-6-12-37-13-15-40-16-14-37)36(2)27(22)35-29(34-26)38-19-32-23-9-11-30-18-25(23)38/h3-5,7-9,11,17-20H,6,10,12-16H2,1-2H3,(H,31,39)(H,33,34,35)/t20-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Procter and Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of JAK3 by kinase-Glo luminescent assay				Bioorg Med Chem Lett 17: 1250-3 (2007) Article DOI: 10.1016/j.bmcl.2006.12.018 BindingDB Entry DOI: 10.7270/Q2H70GMJ
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50201502 (2-(3H-imidazo[4,5-c]pyridin-3-yl)-7-methyl-N-(3-mo...) Show SMILES C[C@H](Nc1nc(nc2n(C)c(cc12)C(=O)NCCCN1CCOCC1)-n1cnc2ccncc12)c1ccccc1 Show InChI InChI=1S/C29H33N9O2/c1-20(21-7-4-3-5-8-21)33-26-22-17-24(28(39)31-10-6-12-37-13-15-40-16-14-37)36(2)27(22)35-29(34-26)38-19-32-23-9-11-30-18-25(23)38/h3-5,7-9,11,17-20H,6,10,12-16H2,1-2H3,(H,31,39)(H,33,34,35)/t20-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Procter and Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of JAK2 by kinase-Glo luminescent assay				Bioorg Med Chem Lett 17: 1250-3 (2007) Article DOI: 10.1016/j.bmcl.2006.12.018 BindingDB Entry DOI: 10.7270/Q2H70GMJ
					More data for this Ligand-Target Pair