BDBM50201598 (S)-3-(2-(2-cyanopyrrolidin-1-yl)-2-oxoethylamino)-3-methyl-N-(2-(pyridin-2-yl)ethyl)butanamide::CHEMBL218026

SMILES: CC(C)(CC(=O)NCCc1ccccn1)NCC(=O)N1CCC[C@H]1C#N

InChI Key: InChIKey=BTCJSOFYQQCEIJ-INIZCTEOSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50201598   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast activation protein alpha (Homo sapiens (Human))	BDBM50201598 ((S)-3-(2-(2-cyanopyrrolidin-1-yl)-2-oxoethylamino)...) Show SMILES CC(C)(CC(=O)NCCc1ccccn1)NCC(=O)N1CCC[C@H]1C#N Show InChI InChI=1S/C19H27N5O2/c1-19(2,23-14-18(26)24-11-5-7-16(24)13-20)12-17(25)22-10-8-15-6-3-4-9-21-15/h3-4,6,9,16,23H,5,7-8,10-12,14H2,1-2H3,(H,22,25)/t16-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description In vitro inhibition of FAP, seprase				Bioorg Med Chem Lett 17: 1274-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.019 BindingDB Entry DOI: 10.7270/Q23T9GV7
					More data for this Ligand-Target Pair
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50201598 ((S)-3-(2-(2-cyanopyrrolidin-1-yl)-2-oxoethylamino)...) Show SMILES CC(C)(CC(=O)NCCc1ccccn1)NCC(=O)N1CCC[C@H]1C#N Show InChI InChI=1S/C19H27N5O2/c1-19(2,23-14-18(26)24-11-5-7-16(24)13-20)12-17(25)22-10-8-15-6-3-4-9-21-15/h3-4,6,9,16,23H,5,7-8,10-12,14H2,1-2H3,(H,22,25)/t16-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description In vitro inhibition of DPP-8				Bioorg Med Chem Lett 17: 1274-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.019 BindingDB Entry DOI: 10.7270/Q23T9GV7
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50201598 ((S)-3-(2-(2-cyanopyrrolidin-1-yl)-2-oxoethylamino)...) Show SMILES CC(C)(CC(=O)NCCc1ccccn1)NCC(=O)N1CCC[C@H]1C#N Show InChI InChI=1S/C19H27N5O2/c1-19(2,23-14-18(26)24-11-5-7-16(24)13-20)12-17(25)22-10-8-15-6-3-4-9-21-15/h3-4,6,9,16,23H,5,7-8,10-12,14H2,1-2H3,(H,22,25)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	118	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description In vitro inhibition of DPP-4				Bioorg Med Chem Lett 17: 1274-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.019 BindingDB Entry DOI: 10.7270/Q23T9GV7
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human))	BDBM50201598 ((S)-3-(2-(2-cyanopyrrolidin-1-yl)-2-oxoethylamino)...) Show SMILES CC(C)(CC(=O)NCCc1ccccn1)NCC(=O)N1CCC[C@H]1C#N Show InChI InChI=1S/C19H27N5O2/c1-19(2,23-14-18(26)24-11-5-7-16(24)13-20)12-17(25)22-10-8-15-6-3-4-9-21-15/h3-4,6,9,16,23H,5,7-8,10-12,14H2,1-2H3,(H,22,25)/t16-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description In vitro inhibition of DPP-II				Bioorg Med Chem Lett 17: 1274-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.019 BindingDB Entry DOI: 10.7270/Q23T9GV7
					More data for this Ligand-Target Pair