BDBM50201703 (1S,2S)-2-bromo-7-oxa-5-aza-bicyclo[3.2.1]octan-6-one::CHEMBL397972

SMILES: Br[C@H]1CCN2C[C@@H]1OC2=O

InChI Key: InChIKey=VVSXVRNUMNINTL-WHFBIAKZSA-N

Data: 9 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50201703   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Pro-cathepsin H (Homo sapiens (Human))	BDBM50201703 ((1S,2S)-2-bromo-7-oxa-5-aza-bicyclo[3.2.1]octan-6-...) Show SMILES Br[C@H]1CCN2C[C@@H]1OC2=O Show InChI InChI=1S/C6H8BrNO2/c7-4-1-2-8-3-5(4)10-6(8)9/h4-5H,1-3H2/t4-,5-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Inhibition of human recombinant cathepsin H				Bioorg Med Chem Lett 17: 1254-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.014 BindingDB Entry DOI: 10.7270/Q2QN66DT
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50201703 ((1S,2S)-2-bromo-7-oxa-5-aza-bicyclo[3.2.1]octan-6-...) Show SMILES Br[C@H]1CCN2C[C@@H]1OC2=O Show InChI InChI=1S/C6H8BrNO2/c7-4-1-2-8-3-5(4)10-6(8)9/h4-5H,1-3H2/t4-,5-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Inhibition of human recombinant cathepsin X				Bioorg Med Chem Lett 17: 1254-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.014 BindingDB Entry DOI: 10.7270/Q2QN66DT
					More data for this Ligand-Target Pair
Dipeptidyl peptidase I (Homo sapiens (Human))	BDBM50201703 ((1S,2S)-2-bromo-7-oxa-5-aza-bicyclo[3.2.1]octan-6-...) Show SMILES Br[C@H]1CCN2C[C@@H]1OC2=O Show InChI InChI=1S/C6H8BrNO2/c7-4-1-2-8-3-5(4)10-6(8)9/h4-5H,1-3H2/t4-,5-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Inhibition of human recombinant cathepsin C				Bioorg Med Chem Lett 17: 1254-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.014 BindingDB Entry DOI: 10.7270/Q2QN66DT
					More data for this Ligand-Target Pair
Cathepsin L2 (Homo sapiens (Human))	BDBM50201703 ((1S,2S)-2-bromo-7-oxa-5-aza-bicyclo[3.2.1]octan-6-...) Show SMILES Br[C@H]1CCN2C[C@@H]1OC2=O Show InChI InChI=1S/C6H8BrNO2/c7-4-1-2-8-3-5(4)10-6(8)9/h4-5H,1-3H2/t4-,5-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Inhibition of human recombinant cathepsin V				Bioorg Med Chem Lett 17: 1254-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.014 BindingDB Entry DOI: 10.7270/Q2QN66DT
					More data for this Ligand-Target Pair
Cathepsin B (Homo sapiens (Human))	BDBM50201703 ((1S,2S)-2-bromo-7-oxa-5-aza-bicyclo[3.2.1]octan-6-...) Show SMILES Br[C@H]1CCN2C[C@@H]1OC2=O Show InChI InChI=1S/C6H8BrNO2/c7-4-1-2-8-3-5(4)10-6(8)9/h4-5H,1-3H2/t4-,5-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Inhibition of human recombinant cathepsin B				Bioorg Med Chem Lett 17: 1254-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.014 BindingDB Entry DOI: 10.7270/Q2QN66DT
					More data for this Ligand-Target Pair
Cathepsin F (Homo sapiens (Human))	BDBM50201703 ((1S,2S)-2-bromo-7-oxa-5-aza-bicyclo[3.2.1]octan-6-...) Show SMILES Br[C@H]1CCN2C[C@@H]1OC2=O Show InChI InChI=1S/C6H8BrNO2/c7-4-1-2-8-3-5(4)10-6(8)9/h4-5H,1-3H2/t4-,5-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Inhibition of human recombinant cathepsin F				Bioorg Med Chem Lett 17: 1254-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.014 BindingDB Entry DOI: 10.7270/Q2QN66DT
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM50201703 ((1S,2S)-2-bromo-7-oxa-5-aza-bicyclo[3.2.1]octan-6-...) Show SMILES Br[C@H]1CCN2C[C@@H]1OC2=O Show InChI InChI=1S/C6H8BrNO2/c7-4-1-2-8-3-5(4)10-6(8)9/h4-5H,1-3H2/t4-,5-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Inhibition of human recombinant cathepsin S				Bioorg Med Chem Lett 17: 1254-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.014 BindingDB Entry DOI: 10.7270/Q2QN66DT
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50201703 ((1S,2S)-2-bromo-7-oxa-5-aza-bicyclo[3.2.1]octan-6-...) Show SMILES Br[C@H]1CCN2C[C@@H]1OC2=O Show InChI InChI=1S/C6H8BrNO2/c7-4-1-2-8-3-5(4)10-6(8)9/h4-5H,1-3H2/t4-,5-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.82E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Inhibition of human recombinant cathepsin L				Bioorg Med Chem Lett 17: 1254-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.014 BindingDB Entry DOI: 10.7270/Q2QN66DT
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50201703 ((1S,2S)-2-bromo-7-oxa-5-aza-bicyclo[3.2.1]octan-6-...) Show SMILES Br[C@H]1CCN2C[C@@H]1OC2=O Show InChI InChI=1S/C6H8BrNO2/c7-4-1-2-8-3-5(4)10-6(8)9/h4-5H,1-3H2/t4-,5-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Inhibition of human recombinant cathepsin K				Bioorg Med Chem Lett 17: 1254-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.014 BindingDB Entry DOI: 10.7270/Q2QN66DT
					More data for this Ligand-Target Pair