BDBM50201745 CHEMBL3926253
SMILES: COC(=O)c1cc2occc2n1CC(=O)c1ccccc1F
InChI Key: InChIKey=AOJLAGANIGJKHU-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
N-acetyltransferase Eis (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50201745 (CHEMBL3926253) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis H37Rv Eis expressed in Escherichia coli BL21(DE3) using Acetyl-CoA as substrate preincubated for 10 mins fol... | ACS Med Chem Lett 7: 1219-1221 (2016) Article DOI: 10.1021/acsmedchemlett.6b00261 BindingDB Entry DOI: 10.7270/Q2251M51 | |||||||||||
More data for this Ligand-Target Pair |